Cytotoxity effect of Hulthemia persica on Hela cancer cells in comparison to Hek
Author(s):
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Because of many side effects of chemical drugs, herbal medicines have been considered for cancer treatment. Hulthemiapersica has five phenolic antioxidants.Therefore, in the present study, its anticancer activity in Helacells was studied in comparison with healthy Hek cells. After collecting the plant, its aerial parts were separated and extracted by percolation method. Hela and Hek cell lines were placed in plates of 96 houses with various concentrations of 8.7, 15.625, 31.25, 62.5, 125, 250, 500, 1000µ g/ mlfor 24, 48 and 72 hours, and the percentage of cell viability Measured by MTT test. Plant extract has no inhibitory effect on Hek cells. However, Hulthemiapersica extract decreases viability rate of the Hela cells at doses of 125, 62.5, 31.25, 15.6, and 7.8 in 24 hours,at all doses in 48 hours and at doses of 1000, 500, 250, 125, 62.5, 31.25 in 72 hours compared to the control group (P<0.05).
Keywords:
Language:
Persian
Published:
Quarterly Journal of Experimental Animal Biology, Volume:7 Issue: 1, 2018
Pages:
81 to 87
https://magiran.com/p1882535
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