Clinical and histopathological Comparison of ketoprofen and midazolam as premedication in pigeon

This study was conducted to compare the clinical and pathological effects of ketoprofen with midazolam as premedication in pigeons. For this purpose, twenty four male adult pigeons with the mean age of two years and weight of 300 gm, were randomly divided into four groups with six individuals per group. Group I was the control group, in which the pigeons were given an intramuscular (IM) injection of ketamine 40 mg/kg body weight. Group II was injected with ketoprofen alone. each pigeon in group III was given an IM injection of ketoprofen at 50 mg/kg body weight and ketamine at 40 mg/kg body weight within 5 min following the first injection. Each pigeon in group IV was given an IM injection of midazolam at 6 mg/kg body weight and ketamine at 40 mg/kg body weight within 5 min following the first injection. Also,. In order to determine the depth of anesthesia in each group and within 5 min from the last injection, various clinical reflexes were evaluated on the body of each pigeon. Also, postmortem examinations were performed to assess in the liver, kidney, Pancreas, Spleen and brain tissues. The results of clinical evaluation in four groups showed that there was significant difference (p<0.05) in the various clinical reflexes between group III, compared with groups I and II and IV.. Based on these result it seems that ketoprofen plus ketamine could be used as a suitable combination for anesthesia of pigeon.