The Effect of Different Doses of Licorice Root with Resistance Exercise on Blood Glutathione Peroxidase Activity and Total Antioxidant Capacity in Sedentary and Overweight Men

The aim of this research was to study the effect of different doses of licorice root with resistance training on blood glutathione peroxidase activity and total antioxidant capacity in sedentary and overweight men. In a semi-experimental trial with double-blind, 90 sedentary and overweight men were divided in six groups of fifteen people: (G1: NRT+SG250mg in the day, G2: NRT+SG500mg in the day, G3: SG250mg in the day, G4: SG500mg in the day, G5: NRT+P250mg in the day and G6: C+P250mg in the day). The resistance training program was conducted for 8 weeks and three sessions per week. Within-group results indicate a significant increase in glutathione peroxidase and total antioxidant capacity in the NRT+SG250mg (P=0.023), NRT+SG500mg (P=0.014) and NRT+P250mg (0.038) group. The highest percentage significant incremental changes of glutathione peroxidase (4.10%) and total antioxidant capacity (29.71%) was related to NRT+SG250mg group. Between-group results showed that there was incremental significant difference between the NRT+SG250mg, NRT+SG500mg, and NRT+P250mg with SG500mg, SG250mg and control groups in the mean concentration of glutathione peroxidase and total antioxidant capacity (P<0.05). Probably, performing resistance training along with taking licorice supplementation can be effective in enhancing the antioxidant status of sedentary and overweight men.