Comparison of Quality of Life and Blood Glucose Control in Type 2 Diabetic Patients with and without Hypogonadism: Case-Control Study

Obesity is considered as a risk factor for testosterone lowering, and low testosterone is a predictor for diabetes mellitus development. The current study compares the quality of life and blood glucose control in type 2 diabetic patients with and without hypogonadism. In this case-control study, 93 male patients with hypogonadism and diabetes who were diagnosed by ADAM questioners and low testosterone level, and 67 patients with diabetes but without hypogonadism were compared in terms of anthropometric, lipid and glycemic control and quality of life. Demographic data were matched in two groups. The anthropometric parameters (waist circumference and body mass index) were significantly higher in hypogonadal patients than patients without hypogonadism (P=0.001 and P=0.024 respectively). Dyslipidemia (P=0.001), fasting blood sugar (P=0.003) and HbA1c (P=0.02) were higher and quality of life was lower (P=0.002) in hypogonadal patients than patients without hypogonadism. Male patients with hypogonadism and diabetes had lower quality of life and less appropriate blood and lipid control, compared with patients with diabetes without hypogonadism.