Serum Vitamin D Level in Patients with Dry Eye Syndrome

Comparison of serum vitamin D levels in patients with dry eye syndrome and control group in patients referring to ophthalmology clinic Al-Zahra of Hospital in 2016. This case-control study was conducted in 2016 on 80 patients with a dry eye syndrome referring to ophthalmology clinic Al-Zahra of Hospital. The data were collected, using information forms and analyzed, using SPSS v.22. In this study, 80 patients were evaluated. 60% of the patients were male and the mean age of the patients was 44.5±11.28 years. Mean vitamin D level was 20.86±10.88 ng/dl, which was not statistically different between the case and control groups. There was not a significant relationship between age and gender of the patients with vitamin D level. Vitamin D level had a significant inverse relationship with OSDI (Ocular Surface Disease Index) (r= -0.48, P=0.002). In this study, the severity of eye dryness based on the OSDI test was inversely related to the serum vitamin D level. Low serum vitamin D level may play a role in pathogenesis of dry eye.