Response of some platelet indices to two-monthresistance training in healthy young men

Disorders of blood hemostasis are associated with the incidence and progression of cardiovascular disease. Physical activity plays an important role in automatic control of the cardiovascular system. The purpose of this study was to evaluate the response of platelet indices to two-month resistance training in healthy young men. In this semi-experimental study, 30 male athletes were randomly assigned to three groups of single-joint and multi-joint resistance training and control group (each group=10). Subjects had no history of specific disease, using any carbohydrate supplement, amino acid, caffeine or antioxidant in the past three months and using alcohol and tobacco. The exercise protocol was run for 8 weeks and 3 sessions per week. Individuals performed special exercises according to their group, and the control group did their daily activities. Before and after the last exercise session, 6-cc blood samples were collected to assess the levels of D-dimer, platelet percentage, mean platelet volume and plasma calcium. The results of this study indicated that there was a significant difference between pre-test and post-test of D-dimer, MPV and PCT (P = 0.001). There was a significant difference between the experimental groups, but these differences were insignificant for calcium (P>0/05). The results showed that the eight-week resistance training caused a significant increase in platelet volume and platelet percentage. An increase in platelet volume is indicative of the increased platelet activation and accumulation. However, the increased D-dimer factor may prevent arterial occlusion of thrombosis. In fact, even moderate intensity exercise may activate some coagulation factors and cause more complications. These results will be helpful in adjusting the intensity of exercise for non-athletes, especially at the beginning of the training period.