Effect of circuit resistance training on serum vaspin concentration and insulin resistance in patients with type 2 diabetes

Insulin resistance has an important role in the pathology of diabetes. Vaspin is a novel adipokine that has a role in increase insulin sensitivity and improve glucose tolerance. There is limited information available regarding the effect of regular exercise, particularly resistance training on serum vaspin concentrations. The purpose of this study was to investigate the effect of Circuit Resistance training on serum vaspin levels, Insulin resistance and its relation In adult men with type 2 diabetes. 18 adult men with type 2 diabetes (age: 48.50±7.73 yr, weight: 79.41±12.60 kg) were randomly assigned to experimental (n= 10) and control (n= 8) groups. Experimental
group participated in a resistance training program (3 days a week for 8 weeks) with an intensity of 50 to 80% of one repetition maximum. Blood samples collected in the 12-hour fasting state before and after training period and levels of vaspin, insulin, glucose and insulin resistance index (HOMA-IR) were measured by ELISA method. After evaluating variables and statistical analysis with t- test, It was found that: After a 8 week resistance training, levels of glucose, insulin and insulin resistance index (HOMA-IR) were significantly decreased (P= 0.040, 0.012 and 0.011, respectively). Whereas, serum vaspin concentration showed no significant changes in resistance trained group when compared with their control groups (p=0/380). Also, no significant correlation between Serum vaspin concentration and levels of glucose, insulin and HOMA-IR were observed between the two groups. The results of the present study suggest that circuit resistance training can be used as an effective factor in improving of insulin sensitivity in type 2 diabetic patients.