Modeling particle deposition in the respiratory system during successive respiratory cycles

In this study, using a 5-lobe symmetric model, total, lobar and generational particle deposition in the lungs during successive cycles is investigated. It has been found that for the particle size between 0.05 and 2 μm and the tidal volumes greater than 1000 ml, considering the effect of successive cycles predicted more deposition fraction per cycle compared to a single cycle up to about 16 percent. The mentioned range of tidal volume is related to light or heavy physical activities. So, it can be understood that people exposed to particulate matter within the mentioned size range, when acting physically, are at more health risk compared not only to the resting state, but also to the same state calculations based on a single cycle. Finally, total and generational remaining mass fraction suspended in the respiratory tract after the completion of each cycle is calculated. This remaining mass fraction turned out to be negligible except for particles between 0.05 and 2 μm.