Effect of hydroalcoholic extract of Pistacia atlantica on testicular tissue and testosterone hormone in Wistar male rat

In recent years, several studies have been conducted on the properties of medicinal plants. One of the native plants of Iran, which has been highly regarded by researchers, is called wild pistachia. Recent internal studies have shown that the leaf extract of this plant can lower blood sugar in diabetic mice. Therefore, the aim of this study was to investigate the effect of the extract of this fruit on testicular tissue.

Male Wistar rats of approximately equal weight were purchased and housed in the University Animal Room. Animals were divided into 5 groups of 5 in 3 experimental groups, one control group and witness group. Experimental groups received Pistacia atlantica extract at doses of 100, 200 and 400 mg orally and the control group did not receive anything during the experiment.

In the control and control group of sperm-producing tubes with high density, short and very regular distance was seen in testicular tissue and no significant difference was observed. While in the experimental group receiving a dose of 400 mg / kg, the number of sperm tubes was reduced. The amount of testosterone in the 400 mg / kg group was lower than in other groups except control.

The results of this study showed that hydroalcoholic extract of Pistacia atlanticaf in mice reduces testosterone levels and loss of normal state in testicular tissue of these mice.