Blood Safety in SARS-CoV-2 Infection

SARS-CoV-2 is a novel infectious agent that rapidly spread from a single city in China to all parts of the world. Right now, the world is facing a major pandemic crisis and every infected patient can infect the other two to three persons. The non-specific symptoms at the early stages of coronavirus 2019 (Covid-19) and also the presence of infected asymptomatic patients result in the absence of accurate estimation of infected patients. Although coronaviruses often affect the upper or lower respiratory tract, viral shedding in plasma or serum can occur and therefore, there is a theoretical risk regarding the transmission of these viruses by transfusion. Experience with other viruses from the corona family group (SARS-CoV and MERS-CoV) tells us that Covid-19 might have a significant impact on blood supply. Until now, SARS-CoV-2 has not been identified as a transfusion transmissible virus and viremia has only been diagnosed in serious patients who would not be allowed for blood donation. In this review article, the safety of blood products during the Covid-19 outbreak is discussed.