Effects of Rosmarinus officinalis commercial extract on some antioxidant and biochemical indices in gold fish (Carassius auratus)

Rosemary (Rosmarinus officinalis) has various biologically active metabolites with antioxidant, anti-inflammatory, anti-cancer and oxidative stress reduction properties.The current study was performed to examine the efficacy of dietary Rosmarinus officinalis commercial extract on some antioxidant and biochemical parameters in gold fish (Carassius auratus). Fish with mean weight 7.6 ± 0.5 g were divided into three groups and fed with 0 (as control group), 1 and 2 g kg - Rosmarinus officinalis extract for 40 days. Based on the results, lower lipid peroxidation product (MDA) was observed in the treatment groups (P<0.05). Meanwhile, activities of some antioxidant enzymes, including catalase, superoxide dismutase and glutathione peroxidase were higher in the treatment groups compared to the control group (P<0.05). Feeding with Rosmarinus officinalis extract also led to a significant decrease in aspartate aminotransferase (AST) (P<0.05), whereas no significant changes were noted in alkaline phosphatase (ALP) and glutathione S-transferase (GST) activities (P>0.05). Therefore, the results of this study show that the administration of 1 and 2 g kg - Rosmarinus officinalisextract had the potential to improve some antioxidant indices, as well as protecting the liver in gold fish and better results require more research.