Correlation of Anti-Mullerian Hormone Level and Antral Follicle Count with Oocyte Number in A Fixed-Dose Controlled Ovarian Hyperstimulation of Patients of In Vitro Fertilization Program

This study was conducted to determine the correlation of anti-Mullerian hormone (AMH) level andantral follicle count (AFC) with oocyte count in women who had received controlled ovarian hyperstimulation in anin vitro fertilization (IVF) program.

We retrospectively gathered the data of 42 patients who underwent IVF during 2005-2017at Aster Clinic in Dr. Hasan Sadikin Hospital and Bandung Fertility Center Limijati Hospital, Indonesia. Details ofthe subjects such as identity, characteristics, history of illness, history of previous therapy, levels of ovarian reservemarkers examined (AFC and AMH), follicle-stimulating hormone (FSH) dose given, and number of oocytes producedwere recorded.

A significant positive correlation between AMH (P≤0.001, r=0.530), AFC (P≤0.001, r=0.687), and AMHAFCcombination (P≤0.001, r=0.652), and the number of oocytes was found at the FSH dose of 225 IU.

AFC and AMH are able to reliably predict ovarian response to FSH.