Assessments the Role of Neutrophil CD64 in Patients with Sepsis in Al- najaf Al- Ashraf Province

Sepsis is a global health matter that provides a considerable danger of death. The main objective of this investigation was to assess the use of CD64 and IgG in the development of bacterial sepsis in patients infected with (Salmonella typhi and Klebsiella pneumonia), Gram-positive bacteria Staphylococcus aureus and the correlation of the marker (CD64) with bacterial sepsis. This study was carried out with a total (140) individual of both sex (100) suspected sepsis patients and (40) healthy group with age ranged (13-65) year enrolled in this study. The result of Microbiological tests was found 40 specimens contain bacterially isolated, was the frequency among 30 (75%) male and 10(25%) female and result revealed that 10 (25%) specimens as a Gram-positive isolate (S. aureus) and 30(75%) specimens as Gram-negative bacteria (S. typhi, K. pneumoniae) while 60 of the rest specimens did not show any growth. While the current study, 30 Gram-negative isolates appeared as a positive result for K. pneumoniae (6) and (24) for S. typhi isolates and represented a major cause for sepsis by using the VITEK system to confirm all bacterial isolates. This study concluded that the sepsis disease influences some risk factor such as age, sex, place of living and the type of bacteria, also affected on immune response represented by CD64.