Comparison of side effects of Tamsulosin and Tamsulosin ER in patients with benign prostatic hyperplasia

In this study, we intend to investigate the effect of continuous-release tamsulosin tablets and tamsulosin capsules on ejaculation.

This study was performed on 120 patients. 66 patients as control group were treated with tamsulosin 0.4 mg capsules and 54 patients were treated with tamsulosin 0.4 mg continuous release tablets and patients were asked about whether or not they had the inability to ejaculate.

The case group consisted of 54 people and the control group consisted of 66 people respectively. The test results indicated that the frequency of ejaculation in the case group and the control group was not significantly different (P = 0.096). Twenty-seven patients had a history of non-ejaculatory complication due to tamsulosin usage (12 of them were in the case group and 15 of them were in the control group).Eight patients in the case group and 4 patients in the control group gained complete recovery from the inability to ejaculate. Therefore, we can conclude that it had a significant difference (p=0.038)

In this study, despite the fact that there was no significant difference in the incidence of no ejaculation, slow-release tamsulosin tablets could improve this complication in People with a history of tamsulosin usage.