Antimicrobial Activity medical plant extracts, Prosopis farcta L. and Datura stramonium L., against Salmonella thyphimurium isolated from poultry in Zabol

The aim of this study was to investigate the antimicrobial activity of Prosopis farcta L. and Datura stramonium L. extracts on Salmonella thyphimurium isolated from poultry in Zabol. The P. farcta and D. stramonium were collected from Collection of medicinal plants, Institute of Agricultural Research at University of Zabol. Strains of Salmonella thyphimurium were isolated from poultry droppings. Antibiotic resistance pattern was determined by Kirby Bauer method. Finally, the minimum inhibitory concentration (MIC) and minimum bactericide concentration (MBC) were determined by microdilution method. The results of this study showed that the lowest inhibitory concentration of Datura extract against Salmonella typhimurium was 3.1 ppm; While the minimum inhibitory concentration for Prosopis extract was 6.5 ppm. Also, the minimum bactericidal concentration of Datura extract was 6.25 and Prosopis extract was 12.5. The results of this study showed that Datura extract was more effective in inhibiting Salmonella bacteria than Prosopis extract. Evaluation of Pearson correlation coefficient between total phenol content, total flavonoids and MIC, and MBC showed an inverse relationship between these parameters. So that the Datura extract, which contained higher total phenol, and total flavonoid, had lower MIC and MBC and therefore was more effective in inhibiting bacteria. The results of our experiments showed that Datura and Prosopis extracts have good antimicrobial effects and can be used to treat infections caused by Salmonella typhimurium in poultry.