The effect of hydroalcoholic extract of saffron petals on egg laying performance of Leghorn chickens and the inhibitory effects of obtained eggs on the growth of MCF-7 and PC3 cancer cells

An experiment was performed to investigate the effect of hydroalcoholic extract of saffron petals on performance indices, egg quality and cancer cells in laying hens. , Five replicates and 10 chicken pieces per replicate were used. Experimental treatments included: treatment: control (basic diet), Timardo: basic diet + 40 ppm saffron petal extract, treatment: basic diet + 60 ppm saffron petal extract, treatment four: basic diet + 80 ppm saffron petal extract. The results of this study showed that feed consumption, conversion ratio, egg weight and egg mass were not affected by the treatments during the whole experimental period (P <0.05). The percentage of egg production was affected by experimental treatments and increased significantly (P <0.05).Yolk weight, shell weight, units, shell thickness and yolk color were significantly affected by experimental treatments (P <0.05). As in the three treatments, the highest yolk height, yolk weight, shell weight and shell thickness were observed. Also, the highest amount of units was observed in treatments one and four and the highest yolk color was observed in treatments three and four. Experimental treatments had a significant effect on growth inhibition of MCF-7 and PC3 cancer cells at different concentrations in concentration-dependent form (P <0.05). The results of this experiment showed that the addition of saffron petal extract improves egg quality and inhibitory effect on cancer cells and the best doses of saffron petal used were observed in treatments three and four.