Assessment of the Pro-oxidant Antioxidant Balance (PAB) in COVID-19 Patients Compared to Healthy Subjects Referred to Masih Hospital
Author(s):
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Objective
Recent studies have shown an increase in the pro-oxidant antioxidant balance (PAB) in patients with Covid 19 and are also associated with exacerbation of clinical manifestations of the disease. What we focused on in the present study was the assessment of the status of PAB level in Covid 19 disease. rMaterials & Methods
In this cross-sectional study, 105 patients referred to Masih Hospital in Tehran in 2021, including 58 subjects with COVID 19 infection and 47 as a control group were studied. The subjects in this study were evaluated for PAB by ELISA method.Results
The mean value of PAB in individuals with and without COVID 19 was 72.77 ± 17.66 units and 66.53 ± 14.30 units, respectively, which was significantly higher in the first group (P =0.049). In patients with COVID 19, there was a significant correlation between PAB and plasma triglyceride level (P=0.011) and there was an inverse relationship between PAB level and blood sodium level (P =0.047). In the subgroup of patients with COVID 19, there was no significant relationship between PAB level and history of hypertension, hyperlipidemia, diabetes and ischemic heart disease.Conclusion
The increase in PAB is quite evident in patients with COVID 19 compared to healthy individuals. There is a significant relationship between PAB and some laboratory markers in these patients such as blood triglyceride levels as well as decreased serum sodium. Therefore, it still seems that theKeywords:
Language:
English
Published:
Journal of Kerman University of Medical Sciences, Volume:30 Issue: 4, Jul-Aug 2023
Pages:
218 to 223
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