Comparative Study of Catheter Structure Types on Venous Thrombosis in Cancer Patients with Peripherally Inserted Central Catheters

Cancer patients with peripherally inserted central catheters (PICCs) are prone to venous thrombosis, occlusion, and o t her complications due to the disease itself, chemother apy, age, and other factor s.

The present study aimed to assess the effect of different catheter materials on thrombosis in cancer patients with PICCs.Meth od s: T he clinical data of 110 cancer patients w ith PI CCs implanted in an outpatient clinic of our hospital fr om Januar y 2018 to June 2019 were collected. The valveless group comprised patients with catheter cancers without valvular structures and high-pr essur e r esistant poly ur ethane mater ial (n=58), and the v alv ed gr oup comprised patients with catheter cancers with valvular structures and high-pressure resistant polyurethane material (n=52).

In the valveless group, 25 (43.1%) patients had total venous thrombosis, which was significantly higher than that of the valved gr oup (n=11 patients; 21.15%) (P=0.028). In 7 out of 11 (78.85%) patients with thrombosis in the valved group, the thrombosis initiation v ein w as the axillar y v ein/subclav ian v ein, while the basilica/brachial vein was the thrombosis initiation vein in 18 out of 25 patients (43.10%) in the valveless group (P=0.043). There was no statistical difference between the two groups in terms of underlying diseases, thrombosis time, and extension in patients with thrombosis(P>0.05).

As ev idenced by the obtained results, the catheter-inver ted cone structure may be a factor of v enous thr ombosis. T herefor e , the str uctur e of catheter s befor e catheter ization should be consider ed and ev aluated.