The Effect of Eight Weeks’ Circuit Resistance Training and Moderate Intensity Continuous Training on Metabolic Indices and Sirtuin1 Serum Level in Women with Metabolic Syndrome

During menopause, women are more exposed to the risk factors of many diseases, including metabolic syndrome, and sirtuin-1 may be involved in this disorder. The aim of this study was to investigate the effect of circular resistance training and moderate intensity continuous training on metabolic indices and Sirtuin1 serum level in women with metabolic syndrome.

This study was conducted as a clinical trial in women with metabolic syndrome in two intervention groups (15 people in resistance training group and 15 people in continuous training group) and a control group (15 people). The intervention group underwent an exercise program for eight weeks and three sessions per week, and the control group had their own routine program. After the last training session, serum levels of Sirtein1 and lipid factors were measured. To analyze the data, t-test and covariance were used at a significant level (P≤0.05).

The results of the t-test showed that there was a significant difference in the intra-group changes of the studied variables (SIRT1, HDL, LDL, TG, FBS, Total Cholesterol) in both exercise groups (P≥0.05), but in No significant difference was observed in the control group (P<0.05). The results of the covariance test showed that there is a significant difference between the three groups in the indices (SIRT1, HDL, LDL, TG, FBS, Total Cholesterol) after the test (P<0.05).

Eight weeks of circular resistance training program and continuous training with moderate intensity has a positive effect on metabolic indices and serum level of Sirtuin1 in people with metabolic syndrome.