Evaluation of Antibody Titer from Newcastle Vaccine and Histological Effect in Sebright Chickens

Newcastle disease (ND) is one of the most important viral disease which make lots of casualty in poultry flocks. Therefor vaccination against ND is the main way to prevents the damages. The aim of this research was evaluation of antibody titer from ND vaccines and histopathological effects in Sebright chickens. In this research, 72 one-day-old Sebright chickens were tested in a completely random format in two groups (with three replications). From day one to the end of period, the breeding conditions were the same for all quails and the differences between the groups were only in the Newcastle disease vaccination program. Vaccination in the first group was based on using: Clone ND vaccine in day old (eye drop), injection of ND/AI + Clone ND (eye drop) in day 8 and using Avinew vaccine (drinking water) in day 15. The second group was considered as the control group (without vaccination). Blood samples were taken at day 25 and 35 and evaluated by HI test. Also, a sample was taken from the intestine and a histopathology specimen was prepared. The results of statistical analysis by Tukey test showed that the mean titer of Newcastle antibody in the vaccinated groups was significantly different (p < 0.01). Also, the results of morphometry and morphology of Newcastle vaccine in the intestinal tissue in the vaccinated groups showed a significant difference compared to the control group (p < 0.05). This study presents as a strategy in terms of antibody production and histological effects after vaccination in Sebright farms.