Polymer nanoparticles as a useful tool for controlled and targeted release of anticancer drugs: A review article

In recent decades, many new methods using nanoparticles to diagnose, deliver, and treat cancer have been explored. Accordingly, the potential of nanoparticles as carriers for the delivery of anticancer drugs is very significant, because the treatment of cancer with nanoparticles has led to the improvement of some drug delivery limitations such as low circulation time and bioavailability, and insolubility in water. In addition, nanoparticles protect drugs against enzymatic degradation and can lead to targeted and / or controlled drug release. One of the most widely nanomaterial type used in nanomedicine is polymer nanoparticles. These compounds have been highly regarded for their biocompatibility and biodegradability, their ability to release drugs in a controlled manner, and their ability to form nanoparticles of ideal size in drug delivery. The present study focuses on the potential of polymer-based nanoparticles that can assist in the targeted or controlled delivery of anticancer agents for cancer treatment.