A review on the role of Malassezia species in patients with atopic dermatitis

Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder characterized by intensely itchy eczema. Sensitivity to Malassezia species may be associated with the severity of AD symptoms. The growth conditions for Malassezia spp. on children's skin are lower than on adult skin, making adults more susceptible to Malassezia. There is a minor suspicion that Malassezia spp. plays a role in AD as it may interact with skin immune reactions and barrier function, and sensitization against this skin-colonizing yeast can be correlated with illness activity. Additionally, antifungal treatment shows beneficial effects in some patients. However, the pathogenetic process and mutual interaction between Malassezia spp. and AD remain relatively unclear, necessitating further research.