Effect of livergol drug on growth performance and preservation of fatty liver in Koi (Cyprinus carpio var. Koi) fed with diets containing different level of fatty.

Livergol drug is made from a herbal extract of Mary Magenta. Milk thistle contains flavonoids and has hepatoprotective effects. The purpose of this study was to evaluate the effects of livergol drug on growth indices and prevention of fatty liver disease in different levels of fat in Koi fish diets. For this experiment, 9 diets of different nutrients were prepared with 3 levels of 0, 0.5 and 1% of livergol and three levels of 5, 10 and 20% fat. The fish were fed for 150 days. After the end of breeding period, fish growth indices (end weight, weight gain, specific growth rate, survival rate and food conversion ratio) and samples of fish liver tissue were investigated. The results of the experiment showed that the final weight, body weight gain, specific growth rate and feed conversion ratio were significant in the experimental treatments (P≤0.05). While survival did not show significant difference among treatments (P≥0.05).The highest growth indices were observed in treatment 8 (fat 20% + livergol 1%). The results of the experiment showed that among all treatments, the highest liver toxicity among the all groups was observed in treatment 6 containing 20% fat and without livergol. The final result of the study showed that in all dietary fat treatments (5, 10 and 20%), adding livergol drug to the diet was probably due to the presence of silimarin reduced liver lesions in Koi fish.