Mean AgNOR count in giant cell containing jaw lesions

Giant cell containing jaw lesions, are similar in most microscopic aspects but different in biological behavior. The aim of this study was to evaluate the biological characteristics of these lesions by using AgNOR as a cell proliferation marker. This descriptive study was conducted on 42 specimens, that were selected by convenient sampling method. The Hematoxylin & Eouzinofyle (H & E) technique were used for lama staining, and they were reviewed by maxillofacial pathologist. The sample blocks were separated and prepared for silver nitrate staining according to Ploton method. AgNOR cell counting was performed for selected visual fields of microscope. The counting was performed by looking at 100 cells in a given field using Nikone YS100 light microscope under 1000x magnifications. ANOVA statistical test was used in order to compare the group mean AgNOR differences. From 42 specimens under investigation, the one and only case of GCT was eliminated. In 21 cases of CGCG, the mean average cell count stained with AgNOR was 0.85 (±0.29). The mean average cell count was 0.76 (±0.32) In eight cases of ABC. In six cases of Cherubis, the average count was 0.87 (±0.10) and in six cases of Brown tumors, the average count of witch was 0.82 (±0.16) for NOR. No significant difference was detected between the mean AgNOR count and their clinical characteristics. In jaw lesions containing Giant cells, no considerable difference in mean AgNOR was detectable.