The Comparison of General Anesthesia Induced by Thiopental Sodium or Propofol with Spinal Anesthesia on the Apgar Score of Neonates Delivered by Cesarean Section.

Regional anesthesia (spinal and epidural) is the method of choice for cesarean surgery, and frequency used during elective cesarean section. In emergent situation, general anesthesia is preferred. The aim of this study was to compare between general anesthesia and spinal anesthesia on neonate's Apgar score delivered by cesarean surgery. In a prospective study, 75 patients who were candidate for cesarean section with term fetus were randomly divided into three groups each 25 patients. The first group underwent spinal anesthesia with 5% Lidocaine, second group received general anesthesia with propofol (2mg/Kg) and third one anesthetized generally with thiopental sodium (5mg/kg). Apgar score of neonates were evaluated and recorded in each group at 1,5,10 and 15 minutes after delivery. Data were analyzed with SPSS.13 software by ANOVA test. Average neonatal Apgar's in first minute of delivery in different groups was as the followings: propofol 9.04±1.31, sodium thiopental 8.80±1.41 and spinal anesthesia 9.12±0.93 (P=0.636).The result of apgar score measurements in each group at fifth minutes after delivery was as the following: sodium thiopental 9.72±0.67, propofol 9.44±0.77 and spinal anesthesia 9.68±0.56 (P=0.289). The results of the same measurements at 10th and 15th minutes are as the following succedingly: sodium thiopental: 9.80±0.65, propofol: 10 spinal anesthesia 9.96±0.20 (P=0.166) and sodium thiopental 9.92±0.28, propofol 10, spinal anesthesia 10(P=0.132). General anesthesia with sodium thiopental or propofol and spinal anesthesia didnt have any significant effect on neonatal Apgar.