Ocular Complications in Renal Transplant Patients

Today’s due to immunological and surgical techniques and increasing complication related to hemodialysis, increasing number of patients scheduled for renal transplant and secondarily ocular complication of immunosuppressive agents increased. Therefore early diagnosis & management of these complications can prevent devastating problems. Our aim was to determine the incidence and type of ocular complication of renal transplant and its correlation with other variables such as, age sex, donor type and duration of renal failure and dialysis. We selected 42 patients without history of any ocular disease and surgery. In each visit, complete eye examination was done. Patients received 500 mg Methyleprednisolone intravenously that started one day before operation and continued 2 days postoperatively, then changed to Prednisolone 20mg/daily. Also postoperatively, Cyclosporine A and Azathioprine started with 5 and 1 mg/kg respectively and continued with tapering doses. The results compared pre and postoperatively with Chi- square and Mann Whitney tests. Total number of patients were 42 cases and donor were three groups: cadaver, relative and non- relative. Of all patients, male & female were 76% and 24% respectively with average age 34.4 year (14-54) with mean 12.6 months follow up (6-24). The most common complication was cataract (45%) but no significant correlation was found between cataract and total dose of steroid, age, sex, duration of dialysis and renal failure. In 7% of patients open angle glaucoma and in 5% bilateral peripheral dendritic herpetic keratitis without inflammation developed. Regarding the ocular complication of renal transplant drugs, it is better that these patients followed regularly to prevent of complication and early treatment.