Evaluation of G6PD Deficiency in Acne Patients
Author(s):
Abstract:
Introduction
Various factors are involved in the pathogenesis of acne vulgaris. Recently, G6PD deficiency has been proposed in the pathogenesis of acne. G6PD has an important role in the oxidant/antioxidant balance. According to this theory, antioxidants are used in the treatment of acne recently. The aim of this study was to evaluate G6PD deficiency in patient with acne vulgaris. Methods
The activity of G6PD enzyme was measured in the venous blood of 82 patients with acne vulgaris of different severity. The fluorescent lamp method was used in order to determine the activity of G6PD enzyme. Results
The mean age of the patients was 25± 3. From 82 patients, the level of the G6PD enzyme was normal in 77 (93.9%) patients. Also, 4 (4.9%) patients had relative G6PD deficiency and 1 (1.2%) patient had severe G6PD deficiency. As the incidence of G6PD deficiency is 5.7% in the normal population, there was no statistically significant difference in G6PD deficiency between patients and the normal population. No significant relationship was found between acne severity and G6PD deficiency. Conclusion
In order to detect the association between acne and G6PD deficiency, other case-control studies with lager sample sizes are recommended.Language:
English
Published:
Iranian Journal Of Dermatology, Volume:13 Issue: 2, Summer 2010
Page:
54
magiran.com/p762602
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یکساله به مبلغ 1,390,000ريال میتوانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
- حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود.
- پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.
In order to view content subscription is required
Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!