A comparative study on the efficacy of intralesional injections of Bleomycin and Normal Saline in treatment of recalcitrant common warts on palm and dorsum of hand

Wart is a common skin disease, and 8% of patients referred to dermatologists suffer from warts. To compare the efficacy of intralesional injections of bleomycin with normal saline in treatment of common resistant warts on palms and dorsum of hands. Patients & This study was a double blind, randomized, controlled clinical trial on 34 patients with common warts on palms and dorsum of their hands. These patients were randomly divided into two groups: 18 patients were treated with intralesional injections of bleomycin and 16 patients were treated with intralesional injections of normal saline. After 3 weeks of treatment, patients were evaluated and in case of unresponsiveness the second injection with the same medication was attempted. This group was visited again 3 weeks later and finally response to treatment ad possible complications were evaluated. In bleomycin group 88.9% and in normal saline group 56.3% remitted (Fisher’s exact test, P<0.05). Intralesional bleomycin is an effective and low risk treatment of common resistant warts on palms and dorsum of hands.