Evaluation of the effect of local dexamethasone injection to reduce inter appointment pain in endodontics treatment

Inflammation is one of the factors causing pain and also the focus of attention of the researchers. Dexamethasone has been mainly used for many years, for its potent anti inflammatory effect and minimal side effect. To a considerably great extent it has been effective in reducing pain. The aim of this study was to determine the effect of local dexamethasone injection to reduce inter appointment pain in endodontic treatment. the nature of this study was randomized controlled single blind trial. It was conducted on 60 patient [men and women] who needed endodontic treatment, on either single of multiple teeth, vital or non vital, maxillary or mandibular and needing multiple appointments. Information needed was got after the injection of 2ml dexamethasone or ringers solution in the buccal vestibule of the involved tooth of the patient with respect to the category the patient carne under. Through a questionnaire given to the patient, questions about personnel demographics, quality and quantity of pain, use and non use of analgesics were asked and the reply collected and analyzed using the software EPI X2 and t-test exam. Results of this study, about the rate of frequency of pain, severity of pain, average degree of pain in the two groups, case and witness at 4 hrs, 8 hrs, 24 hrs and 48 hrs after treatment showed statistical significance. Also comparing on the basis of the analgesics used, adverse effects of the injection, sex, condition of the pulp, vital or non vital, presence or absence of radiolucency at the apex, Significant statistical difference was found in the two groups after treatment. Considering this results, use of local dexamethasone injection at the end of the appointment, causes reduced pain and inflammation in the periapical region of the tooth.