A Comparative Study Between Desmopressim and Imipramine in the Management of Nocturnal Enuresis

Nocturnal enuresis (NE) is a psychosocial problem for children and parents. The incidence of Ne is 20% in 5 years old children. Since no single etiology is found for disorder, various therapeutic modalities have been used. None of which could cure enuresis entirely. Two types of treatment are considered: Pharamacologic & nonpharmacologic. A prospective experimental study in the level of clinical trial in 98 children aged 5-15 years who have NE underwent for 1 month of therapy with imiperamine in 49 and desmopressin in 49 no. of patient treated with imiperamine 36 children have complete response (73%) (all dry bed), at the 3 months follow up 20 children have recurrence. Ammong patients treated with dessmopressin, 31 children have complete response (63%). Recueernce rate after 3 months is 17 cases. Our results didn’t indicate any statistical difference between imipramine & desmopressin in the treatment of N.E. Imipramine is more complicated than desmopressin so that desmppressin is preferred.