Effect of Teucrium polium and Boswellia serrata extracts on cotaneus burn wound healing in Balb/C mice

Message:
Abstract:
Background And Aim
Traditionally, burn wound healing activities have been claimed for Teucrium polium and Boswellia serrata, but there is no evidence in literature for this effect of these plants. Therefore, this study was carried out to investigate the effects of Teucrium polium and Boswellia serrata on burn healing in Balb/C mice.
Methods
In an experimental study, burn wounds were made by placing a hot plate with a surface area of 1.5 cm2 on the back of animals for 10s. Eighty four mice were designated in 7 equal groups. Animals were treated with vehicle or test substances two times per day for 21 days. First to sixth groups received Boswellia 2%, Teucium 20%, Bowellia 20% & Teucium 20%, Bowellia 2% & Teucium 20%, Silver sulfadiazine or Vaseline, respectively. The seventh group received no treatment. Percentage of burn wounds healing and total time required for complete healing were evaluated and compared in different groups. Data were statistically analyzed using ANOVA test.
Results
Results showed that effect of Bowellia and Teucium extract on burn wound healing was statistically significant compared to the control group (P<0.01).
Conclusion
Teucrium polium and Boswellia serrata are clearly effective on burn wounds healing.
Language:
Persian
Published:
Journal of Shahrekord University of Medical Sciences, Volume:12 Issue: 4, 2011
Page:
49
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