Clinical Survey of Patients with Primary Hyperparathyroidism who Underwent Surgery at Taleghani Hospital during 20 Years Ago

Introduction & Primary hyperparathyroidism (PHPI) is a common disease mostly seen in women. Symptomatic PHPT is the predominant form of the disease in many parts of the developing world. In the countries with a screening system, it is usually seen and treated without presenting any symptom. In this study it is tried to define the frequency of different clinical symptoms in these group of patients in compare with other countries. A retrospective descriptive study of records of the patients, who had surgical operation from 1990 to 2010 at Taleghani Hospital, was done. All relevant information (age, sex, clinical presentation and diagnostic imaging procedures) were collected in this survey. Then the data were analyzed by SPSS. 82% of patients were female with the mean age of 47.4 years. None of the patients were without clinical symptoms. Bone disease (62%) and renal disease (45%) were most common manifestation of PHPT. Pathological review of cases revealed adenoma (77%), hyperplasia (12%), double adenoma (4%) and carcinoma (6.7%). PHPT in Iran is a symptomatic disease with predominant features of renal and bone disorders at a much younger age in compare with other countries. In recent decades, the age of becoming afflicted by this disease has increased in Tehran, but it is still lower than that of the west.