Effects of fasting in the holy month of Ramadan on the uric acid, urea, and creatinine levels: A narrative review

Fasting during the month of Ramadan is one of the Five Pillars of Islam. During this holy month, healthy Muslims abstain from eating, drinking, and smoking from dawn to dusk. Although fasting is obligatory for every adult Muslim, if it has hazardous effects on the body, it is prohibited. Due to some Islamic principles, patients are exempted from fasting; however, due to the willingness of some individuals to fast, there are concerns about its effects on urea, uric acid, and creatine levels. Atypical levels of these compounds can cause serious disorders or indicate abnormal renal function. The present narrative review is aimed to investigate the effect of abnormally high levels of urea, uric acid, and creatinine on one’s health and effects of fasting during Ramadan on these indicators. Articles were searched from PubMed, Elsevier and Google Scholar and then they were evaluated. It can be concluded that fasting does not have any adverse effects on the urea, uric acid, and creatinine levels according to the above-mentioned studies.