Application of Poly(nicotinamide) Modified Carbon Paste Electrode Sensor for the Electrocatalytic Determination of Acetaminophen and Folic Acid

Poly (nicotinamide) modified carbon paste electrode (poly-NA MCPE) was fabricated for the electrocatalytic determination of acetaminophen (AC) and folic acid (FA) by using cyclic voltammetric method. Compared to bare carbon paste electrode (BCPE) the poly-NA MCPE showed better electrocatalytic performance towards the oxidation of AC in phosphate buffer solution (PBS) of pH 7.4. Under the optimized experimental conditions, the influence of scan rate and concentration were studied. The detection limit of AC was calculated to be 0.072 mM by CV technique, in a linear concentration range of 20.66 to 119.04 μM. The poly-NA MCPE was used for the simultaneous determination of AC and FA in a binary mixture by CV and differential pulse voltammetric (DPV) technique.