The effect of regular aerobic training on beta cell function and serum insulin in sedentary male's smoker

Previous studies have shown that nicotine can affect beta cell function and insulin secretion in cigarette smokers. The aim of present study was to evaluate the effect of 10 weeks aerobic exercise on insulin and beta cell function in smokers. In this semi-experimental study with pre and post-training design, a total of 36 adult smoker men aged 41±2.5 years were selected into either exercise (n=18) or control (n=18) groups. Exercise participants underwent a 10-weeks supervised aerobic training intervention (3 days/weeks for 45-60 min at 60-80% HR max). Pre (baseline) and post training of fasting glucose, insulin serum and beta cell function were measured of two groups. Aerobic intervention resulted in significant decrease in fasting glucose. In addition, aerobic training induced a significant increase beta cell function and serum insulin in exercise group. The control group exhibited no significant change in any variables. Long term aerobic training is associated with improvement in glycemic profile in male’s smoker. The benefits effect of aerobic intervention on glucose homeostasis in cigarette smokers may be attributed to improved beta cell function.