Performance Assessment of the Acute Physiology and Chronic Health Evaluation IV Scoring System in Outcome of Patients fallowing Acute Poisoning

The present study aims to assess the ability of the acute physiology, chronic health evaluation IV (APACHE IV) scoring system to predict in-hospital mortality of intensive care unit (ICU) patients with acute poisoning. Using data from 622 consecutive ICU admitted poisoned patients, Loghman-e-Hakim Hospital, Tehran, during May 2015-April 2016. Various statistical tools used to assess the correlation, significance, and predictability. Overall APACHE IV scoring system was statistically significant (P=.001). Death rate prediction, increased from 79.4% to 86.8 % by model, with SMR =0.83%. A meaningful association between APACHE-IV score and the risk of mortality with good discrimination and, calibration (p value of 0.978) was evident. The present study demonstrates that the APACHE IV system performs acceptably in our patients with acute poisoning and can be utilized as a performance assessment tool in poisoning centers.