Assessment of hepatitis C risk factors in center of Iran: A case–control study
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background
Hepatitis C virus (HCV) infections remain as one of the major public health problems worldwide. Te current study aimed at investigating the potential risk factors of HCV+ in a sample of Iranian patients.
Materials and Methods
In a case–control study, 436 HCV?infected patients and 531 age?matched HCV antibody negative controls were recruited in a central region of Iran. Sociodemographic characteristics, blood and therapeutic factors, underlying diseases, and behavioral risk factors were evaluated
through a standard checklist and compared between two study groups.
Results
Although among studied potential risk factors, many of them were signifcantly associated with infected with HCV; however, in multivariable logistic regression model in the presence of other variables being male gender (odds ratio [OR]: 4.1; 95% confdence interval [CI]: 2.2–7.8), illiterate or less educated (OR: 62.64; 95% CI: 5.94–660.35), having history of intravenous (IV) drug addiction (OR: 33.0; 95% CI: 5.43–250.0), and tattooing (OR: 14.29; 95% CI: 1.82–90.91) increased risk of infection with HCV.
Conclusion
In total, the current case–control study documented that socioecomical factors including economical state, marital status, education, and ethnicity and also other expected factors such as hospitalization, imprisonment, dialysis, tattooing, needle sharing, IV drug abuse, and extramarital sexual relationship represent an important source of HCV infection among adults in a central region of Iran. Tus, we suggest further considerations for prevention of HCV infection as most of related factors are preventable by close considerations
Language:
English
Published:
Journal of Research in Medical Sciences, Volume:23 Issue: 10, Oct 2018
Page:
1
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