Correlation Between Asymptomatic Persistent Microscopic Hematuria and Reflux Nephropathy

Asymptomatic persistent microscopic hematuria is one of the common symptoms in children with kidney disorders and may be one of the most important signs of glomerular damage. Vesicoureteral reflux (VUR) also is one of the common disorders in children that causes scarring, secondary lesions, and subsequent problems, including hypertension, chronic renal failure, and end-stage renal disease (ESRD). This is a case-control study that was conducted on 100 children with VUR (50 children with reflux nephropathy as the case group and 50 children without reflux nephropathy as the control group) at Amirkabir Hospital, Arak, Iran. The frequency of asymptomatic persistent microscopic hematuria was evaluated in both groups of children. The mean age of the children in the case group was 2.93 ± 2.30 and in the control group was 3.46 ± 2.68 years old (P = 0.268). Thirty-four percent of the case group and 14% of the control group were males (P = 0.019). In addition, 22% of children in the case group and only 8% of children in the control group showed asymptomatic persistent microscopic hematuria (P = 0.049). According to the results of this study, it seems that the asymptomatic persistent microscopic hematuria is more in children with reflux nephropathy.