مجله زنان مامائی و نازائی ایران
سال هجدهم شماره 184 (هفته دوم اسفند 1394)

The effectiveness of letrozole and cabergoline for treatment of ovarian hyperstimulation syndrome (OHSS) has been evaluated and proved separately in previous studies, but there is no study to compare the effectiveness of these two drugs, therefore, this study was performed with aim to compare the effect of letrozole versus cabergoline for prevention of ovarian hyperstimulation syndrome (OHSS) in patients under ovulation induction treatments and IVF cycles.
This randomized, double-blind clinical trial was performed on 60 patients with complain of infertility who referred to Milad infertility center in Mashhad from April 2014 to July 2015 and were treated with ovulation induction drugs and developed the first sign and symptoms of ovarian hyperstimulation syndrome (OHSS). By randomized block method, the patients were divided into cabergoline and letrozole groups. Then, the researcher administered 5 mg letrozole to the patients of letrozole group after pick up for two weeks. Similarly, the researcher administered 0.5 mg cabergoline to the patients of cabergoline group from the day of pick up for 8 days. Then, the patients were weekly evaluated for 4 weeks in terms of any development in signs and symptoms of OHSS. Data was analyzed by SPSS software (version 11.5) and Chi-square, independent-t, and reapeted measures tests. P
There was no significant difference between two groups in terms of type of infertility (primary or secondary) (P=0.562), history of polycystic ovarian syndrome (P=0.584) and history of ovarian hyperstimulation syndrome (P=1.000). Among 60 patients, 25 (42%) had no need to hospitalization and were treated as outpatient, but 35 (58%) were hospitalized for 1 to 8 days during the study. There was no significant difference between two groups in terms of duration of hospitalization (P=1.000), Additionally in terms of clinical improvement during weekly follow-up (P=1.000).
Letrozole has similar effect as cabergoline for prevention of ovarian hyperstimulation syndrome (OHSS).

Post-Dural puncture headache (PDPH) is one of the common complications of spinal anesthesia, especially after cesarean section. It is better to treat this headache by non-pharmaceutical methods. One of the non-pharmaceutical pain control methods is the use of acupressure. But so far, its impact on headache after spinal anesthesia has not been studied. Therefore, this study was performed with aim to evaluate the effect of acupressure and touch on headache caused by spinal anesthesia after cesarean section.
This randomized clinical trial with control group was conducted on 90 patients who underwent cesarean section by spinal anesthesia in Semnan Amir AlMomenin (A) Hospital in 2015. These patients were randomly divided into acupressure, touch and control groups. Pain severity was measured by Visual Analog Scale (VAS). Then, changes of pain severity pre and post intervention was measured and recorded. Data was analyzed by SPSS software (version 16) and Pearson and Spearman correlation coefficient tests, Kruskal-Wallis test, ANOVA and paired t-test. P The mean of pre-intervention PDHP scores in the control, touch and acupressure groups were 4.43±1.47, 4.48±1.65 and 4.73±1.72, respectively that no statistically significant difference was observed between three groups in terms of mean of pre-intervention PDHP scores (P˃0.05). After the intervention, there was a statistically significant decrease in mean pain score in acupressure and touch groups in comparison with control group (P˂0.001). Also, after intervention, there was a statistically significant decrease in mean of headache scores in the acupressure group compared with touch group (P˂0.001).
Comparing with touch, acupressure was more effective for headache-relieving after spinal anesthesia in women undergoing cesarean section. Therefore, it is suggested that acupressure along with other conventional treatments be used to control and treat such headaches

Osteoporosis is a common problem in health systems and in fact, it is a hidden epidemic. Only the early diagnosis can prevent its complications. Therefore, this study was performed with aim to evaluate knowledge, attitude and performance of high school girls about osteoporosis.
This cross-sectional study was performed on 715 adolescent female students who were educating in six high schools of Boushehr. Data were collected through a questionnaire which included 52 questions about demographic information, knowledge, attitude and performance of adolescent regarding osteoporosis risk factors (physical activity, nutrition, and smoking). Data were analyzed using SPSS software (version 16) and chi-square test. P 621 students (86.9 %) had desirable and 94 (31.1%) had moderate knowledge regarding Osteoporosisrisk factors. 662 of participants (92.6%) had desirable and 53 (7.4%) had moderate attitude and none of them had poor attitude about the factors effective on osteoporosis. In terms of physical performance, 2 students (0.3%) haddesirable, 143 (20%) moderate, and 570 (79.7%) had poor physical activity. There was no significant relation between knowledge and performance (P=0.18) and also between attitude and physical activity (P=0.42).
The girls who participated inthis study had desirable knowledge and attitude regarding osteoporosis, but most of them had poor performance in terms of physical activity. It is suggested that parents and managers design appropriate program to increase physical activity ofadolescents.