فصلنامه طب مکمل
سال سیزدهم شماره 3 (پیاپی 48، پاییز 1402)

Treating diseases depends on the type of relationship between physician-patient and dissatisfaction with this relation by the patients brings about using traditional medicine. The main purpose of this research is to investigate the relationship between dissatisfaction with the physician-patient relationship and the use of traditional medicine.

This research has been done using a survey method. The population is people aged 18-65 living in Ahvaz City, in 2019-2020, that 345 were determined as the sample size using Cochran's formula and were selected by means of a multi-stage random sampling method. The research tools are two researcher-made questionnaires including the “physician-patient relationship” and the “use of traditional medicine”. In the process of collecting data, the respondents were informed of the research objectives and they participated in the research if they were written consent. To examine the relationship between the two variables of physician-patient relationship and inclination to traditional medicine the correlation matrix and linear regression have been employed using the SPSS software version 25.

In general, 174 women and 171 men participated in this research. 139 were single and 206 married. In terms of ethnicity, 111 were Lor, 117 Arab, and the rest were Fars, Turk, and Kurd. The results of the regression analysis showed that the dissatisfaction with the physician-patient relationship significantly increases the use of traditional medicine (Beta=2.27, T=2.27, Sig=0.000).

Based on the results, the more people dissatisfy with the physician-patient relationship, the more they are inclined to use traditional medicine.

Changes in gene expression and protein expression of the spinal-blood barrier play an important role in the transmission and development of neuro-inflammatory responses. In order to increase the knowledge related to the role of environmental interventions affecting the tight junction and adhesive proteins of this barrier, this study investigated the effect of four weeks of resistance training and date pollen/testosterone extract on gene expression and protein expression of occludin and cadherin in male rats.

In an experimental design, 30 male Wistar rats randomly divided into 6 groups: Control; Resistance training; DPP extract; Testosterone; DPP extract+ resistance training; Testosterone+ resistance training. The amount of 100 mg/kg date pollen extract was fed to mice by gavage for 4 weeks. Also, synthetic testosterone with a dose of 2 mg/kg was used subcutaneously as a positive control. Resistance training consisted of a four-week increasing training period on a 50-step ladder with 8 to 12 repetitions per session. After the intervention, gene expression was measured by RT-PCR method and protein expression was measured by western blot method.

Four weeks of resistance training caused a significant increase in occludin gene expression (P=0.010) and cadherin (P=0.015); While it had no significant effect on the protein expression of occludin (P=0.404) and cadherin (P=0.647). Also, the gene expression level of two proteins increased significantly under the influence of date pollen extract and testosterone (P<0.05).On the other hand, the protein synthesis rate of occludin (P=0.016) and cadherin (P=0.012) was increased only in the group receiving synthetic testosterone. Despite the fact that the highest level of gene expression of two proteins was observed when the interventions were combined simultaneously, there was no statistically significant difference between their synergistic effects (P=0.059). However, the highest expression of occludin and cadherin protein occurred when resistance training was combined with testosterone supplementation (P<0.05).

The results of this study showed that DPP extract is superior to other interventions for increasing the gene expression of occludin and cadherin proteins of the blood-spinal barrier and testosterone for increasing the expression of these proteins. The combination of these interventions with the double promotion of the signaling process of gene and protein expression will maintain the integrity and reduce the permeability of the blood-spinal cord barrier in healthy male animal samples.

Infertility is a public health problem worldwide. Infertility is associated with many psychological problems. The reality therapy is one of the newest approaches and psychological therapies. The purpose of this study was to investigate the effect of reality therapy on psychological well-being of infertile women.

The present study is an interventional study with a pre and post-test method, in order to investigate the effect of counseling based on reality therapy on the psychological well-being on 38 infertile women who referred to Arak University Jihad Infertility Center. After obtaining informed consent and with available sampling, out of 95 infertile women who met the criteria to enter the study, 40 who scored less than 54 on the RIF psychological well-being questionnaire (pre-test), were randomly placed into two groups of 20. The intervention group received 8 reality therapy counseling sessions and the control group received routine care. After the intervention, the RIF questionnaire was again provided to the two groups (post-test). Data were analyzed by chi-square, independent t and paired t tests in SPSS version 25 software.

The mean age of women was 26.9 ± 4.9 years. The results showed that the mean score of psychological well-being (Respectively (48.7 ± 17.48 63.97± 5.31 P=0.0001 ).as well as all the components of psychological well-being, including independence, mastery of the environment, personal growth, positive relationship with others, purposefulness and self-acceptance, increased significantly in the intervention group compared to the control group (P=0.0001).

According to the findings of this research, reality therapy counseling can be effective in improving the psychological condition of infertile women.

Moringa (Moringa spp.) is a native shrub with a high nutritional value found in the mountains and hills of southeastern regions in Iran, extending from Hormozgan, Bashagard, to the border of Pakistan. This valuable plant has not been properly known and identified.

The study followed a field fashion using checklists, observation along with participation, and interviews, as well as articles and books. Data were collected, in the regions of Hormozgan and Sistan and Baluchistan through in-person questions, research, and contact with the study population and elderly individuals, in the fall and winter of 2019. 40 checklists were collected from people living in the study areas. Data were analyzed using SPSS software, Mean and standard deviation were used to describe continuous variables and categorical variables were reported with number and percentage.

The age mean of the participants was 47.82 ± 14.91 years ranging from 23 to 80 years. In both regions, Moringa was used mostly as food (81%), and oil as a massaging alternative (19%). A total of 90.5% used the plant as a seasoning and food additive, oil, tea, and 9.5% used it as ointment and poultice to heal wounds. 85% dried consumption while 15% of the locals used it freshly.

The local uses of moringa plant were mostly as a seasoning and food additive, oil and tea. In less cases, it was used as ointment and poultice to heal wounds.

Autism is a highly variable neurodevelopmental disorder, formally called autism spectrum disorder, characterized by deficits in social communication, social interaction, and repetitive or restricted behavior patterns. This study aims to investigate the temperament of autism spectrum patients from the perspective of Iranian medicine, so that by helping to understand the causes of the temperament of this disease, a new step can be taken in the direction of prevention and treatment of this disorder.

This research is a descriptive cross-sectional study. The study subjects were 60 patients referred to Golhai Behesht Autism Rehabilitation Center in Qom city in 1401, who were randomly selected. Dr. Salmannejad's temperament questionnaire was used to determine the temperament of the participants in the study. SPSS version 25 software was used for data analysis.

The findings showed that the highest frequency of mixed temperament among children on the autism spectrum was related to cold and dry temperament with 40% and the highest frequency of singular temperament was related to dry temperament with 78%.

According to the findings of this research, autism spectrum patients have a cold and dry temperament. Clinical studies are suggested to investigate the effectiveness of therapeutic interventions in cold and dry mood for the recovery of these patients.

Traditional medicine reported the appropriate analgesic and anti-inflammatory effects of Malva sylvestris, The anti-inflammatory effect, which was proved by literature, made it likely that the plant would be effective in pain modulation. Therefore, the effect of its hydro-alcoholic extract on the analgesic effect of morphine was assessed for reducing morphine dosage.

Pain intensity was assessed using Tail Flick test at spot heat of 55°C and cut off time of 10 seconds on adult male rats. An appropriate dose of morphine to cause analgesia was determined intraperitoneally using dose-response method. The analgesic effect of different doses 100,200,400 and 600 mg/kg of Malva sylvestris extract and the effect of the doses on the analgesic property of an appropriate dose of morphine (2.5mg/kg) were examined.

The best analgesic effect with the ability to increase the threshold for occurrence of tail painful reflex was related to dose 400 mg/kg of the extract, which its highest analgesic effect was observed in minute 45. Administration of the most effective dose of the extract with morphine significantly (pvalue<0.05) increased morphine’s analgesic effect. Naloxone administration, 15 minutes before administration of this dose, could significantly (pvalue<0.05) decrease its analgesic effect.

Hydroalcoholic extract of Malva sylvestris (HEMS) is capable of increasing morphine’s analgesic effect. Some of this effect is through its effect on opioid receptors, which are inhibited by Naloxone as an antagonist of morphine that is probably one of its analgesic mechanisms.

Premenstrual syndrome is a set of symptoms that affect the quality of life, family relationships and social functioning of women. One of the recommended methods to control symptoms is lifestyle modification, which is emphasized by Persian medicine. Motivational interviewing helps to modify lifestyle by creating self-care behaviors. The present study was conducted with the aim of determining the effect of motivational interview with the content of principles of Hefz – Alsehe in Persian medicine on premenstrual physical and psychological symptoms.

A randomized controlled trial was started on 21/01/2022 in selected medical centers in Zanjan. 50 women who had premenstrual symptoms after obtaining written informed consent were divided into two intervention (25) and control (25) groups with random allocation. The intervention was five individually and virtually sessions of motivational interviews based on the principles of Hefz-Alsehe in Persian medicine. Control group did not receive any intervention. The premenstrual symptoms screening tool was completed by the participants in three stages before the intervention, immediately after the intervention and three months follow-ups. Data were analyzed by independent t-test, chi- squared test, repeated measurement test and Benferroni's post hoc test in SPSS.

In the intervention group, the mean changes (standard deviation) of psychological symptoms in pre-test 22.57(8.053), post-test 16.95(7.406) and follow-up 11.67(5.893) and the effect of symptoms on daily life activities the pre-test 10.05(2.356), post-test 5.24(2.624) and follow-up 4.52(2.694) with (P<0.01) was significant. Changes in physical symptoms were not significant.

According to the findings of the study, motivational interview focused on some principles of Hefz – Alsehe in Persian medicine can be used to improve the psychological symptoms of PMS and the impact of symptoms on daily life activities.

Sleep-disturbances in hospitalized school-aged children with Acute Lymphoblastic Leukemia(ALL) are a common complaint that leads to a decrease in the quality of life of these children. The aim of this study was to investigate the effectiveness of orange essential oil aromatherapy on sleep-disorders in children with ALL.

This quasi-experimental research was conducted with two groups of 30school-aged children with ALL hospitalized in Shafai-Hospital in Ahvaz city, by sampling using the available method and with a score of more than 41 from the Children’s Sleep Habits Questionnaire(CSHQ), in 2014 with obtaining written consent. Sampling and intervention in order to prevent the interference of the smell of essential oil was done first in the control group by inhaling 2drops of placebo, then in the test group by inhaling 2drops of orange essential oil for one week and at the end of the week, CSHQ was completed again. The obtained information was analyzed by SPSS statistical software and paired t and independent t tests.

The analysis of data after aromatherapy shows a statistically significant difference in most of the sleep-disorders of the experimental group, including sleep-duration(P=0.001). Sleep-anxiety(P=0.01) and insomnia(P=0.001) compared to sleep-disorders in the control group(P>0.05). The analysis of data before and after aromatherapy showed that the difference in the average scores of most sleep-disorders such as sleep-duration(1.53±0.44), sleep-anxiety (5/03±1/29) and insomnia(9/9±2/98) were significant in the test group(P<0.05) and not significant in the control group(P>0.05).

Aromatherapy with orange essential oil can improve the sleep-disorders of hospitalized school-aged children with ALL and ultimately improve the quality of life of these children.