فهرست مطالب سعید آل رسول

Study Type: Case - Control Study | Subject: Gynecology | Received: 2014/08/9 - Accepted: 2014/08/9 - Published: 2014/08/9 Article abstract: Thrombophilia is characterized by increasing blood coagulability. It causes preeclampsia and repeated abortions. This study was done to determine the corrolation of coagulation factors deficiency with preeclampsia. This case-control study was carried out on 142 pregnant women with preeclampsia as caess and 142 pregnant women without preeclampsia as controls. Coagulation factors including Prs, prc, and anti-thrombin-3 were measured using ELISA and chromogenic methods. Prs deficiency was found in 2 (1.4%) and 6 (4.2%) of cases and controls, respectively. This difference was not significant. Prc and anti-thrombin- 3 deficiencies was not found in cases and controls. There is not any relation between deficiencies of coagulation factors with preeclampsia.

Early diagnosis of preeclampsia could make early intervention and on time delivery possible and decrease the risk of progressing into severe preeclampsia, pulmonary edema, eclampsia, stroke, and even death. Factor V Leiden (FVL) during pregnancy could lead to placental clotting events and fetal and maternal complications such as preeclampsia and recurrent miscarriage. This study was designed and conducted to investigate the association of FVL deficiency with preeclampsia and eclampsia in pregnant women. In this case-control study, 142 pregnant women with preeclampsia (since the 20th week of pregnancy onwards) referring Maternal Clinic of Hajar Hospital, Shahrekord were selected as control group after clinical, laboratory examinations and according to specialist viewpoint and 142 pregnant women with normal blood pressure were selected as control group. After obtaining consent and completing relevant questionnaire, 4cc blood was taken from patients and FVL rate was measured. The patients after six months were followed up in view of blood pressure. The rate of FVL deficiency in the pregnant women with preeclampsia was 5(3.5%) cases while no case was observed in healthy pregnant women group (p=0.03). In case group compared to control group, preeclampsia history contributed to development of current preeclampsia (p=0.001). In addition, in case group the prepregnancy BMI was significantly higher compared to control group (p=0.001). In view of significant difference of FVL deficiency between pregnant women with preeclampsia and healthy women in the region under study, it seems that measurement of this factor help unpleasant complications of vascular disorders derived from this factor deficiency during pregnancy decrease.

Carpal tunnel syndrome is a common condition in which the median nerve passes through the carpal tunnel is compressed. Then، gradual paralysis occurs. This study aimed to compare patient outcomes after surgery for carpal tunnel syndrome in both groups with and without splint.. This study was conducted in Isfahan University of Medical Sciences، Iran، in Kashani hospital during 2011. 64 patients underwent surgery for carpal tunnel syndrome were selected and randomly divided into two groups of 32. For the first group، splints were considered after the surgery and for the second group، as the control group، splint was not given. Patients within 3، 6 and 12 weeks after surgery were followed and healing in the sense of motion and pain based on the visual analogue scale (VAS) measures were examined. Sensory conflict scores at the 3rd and 6th weeks in the group with splint were higher than the group without it; but، 12 weeks after the treatment، the results were identical. In any cases، motor involvement was not seen. At the 3rd week after the treatment، the mean pain score in the group without splint was higher than with splint group. The results of the 6th week after the treatment in both groups were almost identical; but، at the 12th week after the treatment، changes in pain intensity was not significantly different between the two groups (P = 0. 97). Splinting after the surgical release of the median nerve probably causes a delay in the recovery of sensory، motor and pain; but due to the effect of material of used splint، the result is still uncertain and further broader interventions needs to be done in this regard.