فهرست مطالب بیتا محمدی

Fall is the most common and serious problem that occurs in Aged ,which has significant effects on their health and quality of life.The purpose of this study was to determine the relationship between fear of falls and depression in Aged diabetic patients in Amol hospitals. This is a descriptive-analytic study that was conducted in 2018. The corpus of study involved 191 Aged  diabetic patients aged 60 years and over. Sampling method was available. The instrument for data collection was demographic characteristics, FES-I scales, a fifteen-item questionnaire GDS and AMT and ADL.  Data analysis was done by using descriptive and inferential tests and was shown via SPSS software. Most participants (50.3%) were female. The average age of participants was 70.4 ± 6.6 years. Based on the findings, the average of fear of falling was (25 ± 8.7) and average of depression was (6.7 ± 2.1). The results of Spearman's correlation coefficient showed a significant positive correlation between fear of falling and depression (p = 0.001, r =0.234). So that the fear of falls of the Aged were increased, their depression also increased. The results of this study showed that there is a significant relationship between the fear of falling and depression in Aged people. So, psychological treatments and exercise should be done to reduce their fear of falling.

Preterm labor is a major risk factor of mortality and morbidity in newborns and fetuses. Low birth weight is also a risk factor for mortality and various neonatal diseases. This study aimed to determine the association between the CRP levels in first trimester of pregnancy with low birth weight and preterm labor.Methods & Materials: In this prospective cohort study, we measured serum CRP levels in 400 pregnant women up to 20 weeks of gestation. All participants were followed up to delivery. Preterm labor was defined as delivery before 37 weeks of gestation. Low birth weight was defined as weight less than 2500 g at birth. Statistical analysis was done using Chi-square, Logistic regression, and ROC curve. P-values less than 0.05 were considered to be significant. After controlling for the effects of age above 35 years, mother's occupations, history of preterm labor, socio-economic status, history of abortion, primiparity, and passive smoking, logistic regression analysis showed statistically significant relationship between the CRP and preterm labor (P-value=0.000, OR=1.24, %95 CI=1.11-1.38). However, there were no significant relationships between the CRP levels with other factors. Using Roc curve, we determined CRP cut-off point level for preterm labor. With 81% sensitivity, and 64% specificity, CRP cut-off point was 3.45 mg/l. After controlling for the effects of low socio-economic status, history of LBW, history of abortion, gravidity, primiparity, and passive smoking, logistic regression analysis showed statistically significant association between the CRP levels and LBW (OR=1.31, CI %95=1.08-1.59, P=0.005). However, there were no significant relationships between CRP levels with other factors. CRP cut-off point level for LBW was determined using Roc curve. With 87.5% sensitivity, and 74% specificity, CRP cut-off point was 4.75 mg/l. It seems that the inflammatory marker, CRP, can be used to identify women who are at high risk for preterm labor and LBW. However, larger studies are needed to establish this relationship definitively

Preeclampsia is one of the most common medical complications during pregnancy that can be a major cause of prenatal morbidity and mortality. One of the most studied biomarkers in the prediction of preeclampsia is C-reactive protein. The objective of this study was to assess the relationship between maternal serum CRP concentrations in early pregnancy and the onset of preeclampsia during the gestational period. In this prospective cohort study, serum CRP levels were measured in 400 pregnant women in their 20th week of gestation. They were all followed up till delivery. The data were finally analyzed statistically. After controlling for the effects of maternal age (< 19 and > 35 years), multiple regression analysis for primiparity, supplementary calcium intake, BMI and CRP depicted a statistically significant relationship between CRP levels and mild (OR = 1.71, 95% CI = 1.39 - 2.11) and severe (OR = 2.45, 95% CI = 1.80-3.34) preeclampsia onsets. Among all the aforementioned variables, only supplementary calcium intake was significantly effective in the prevention of preeclampsia. In ROC curve analysis, the CRP cut-off point in moderate preeclampsia was 5.35 mg/l (with 94% sensitivity and 81% specificity), and in severe preeclampsia it was 5.45 mg/l (with 94.4% sensitivity and 82.5% specificity). It seems that CRP can help identify pregnant women who are at high risks of preeclampsia but larger studies are needed to establish a definitive relationship.