فهرست مطالب زهره حیدرنژاد

Coronary artery disease (CAD), is a leading cause of mortality and morbidity in the world and more focused among the researchers. For this reason, novel risk factors for CAD, such as serum iron in the form of serum ferritin levels have been emphasized. Excessive serum iron can increase risk of CAD by the production of free radicals and incorporation into lipid peroxidation.
To investigate the relationship between serum ferritin level and severity of obstructive CAD.
This analytical cross-sectional study was conducted on 400 patients with CAD, referred to Rasht Heshmat Heart Hospital from September of 2014 to March of 2015. Demographic information, serum ferritin level with other blood markers was collected before angiography and the severity of vessel involvement was evaluated afterwards. Data analysis was done using Mann-Whitney, Kendall tau and Spearman correlation coefficient tests.
The median age of patients was 58 years and 56% were male. The median of serum ferritin level in women and men was 74 and 95 µg/dl, respectively (p.05 for all)
In this study, no significant relationship was observed between serum ferritin level and severity of obstructive CAD. Further investigations are needed to consolidate the finding.

Vitamin D deficiency is the most common nutritional deficiency as well as a basic factor for normal bone growth. Increasing evidence indicates that the vitamin D contributes to normal glucose homeostasis and its deficiency is associated with impaired insulin secretion, as demonstrated in some reported studies. However, very limited studies and some even with conflicting results, have addressed the association between the level of 25-hydroxyvitamin D in circulation and the risk of gestational diabetes.
Objevtives: Investigating the association between vit D deficiency and gestational diabetese.
This case-control study was conducted on 157 women aged 15-50 years, referred to Rasht alzahra Hospital. Demographic data and medical history were collected. In doing so, for evaluation of gestational diabetes, glucose challenge test was done. Also, vitamin D level measurement was performed using Diasorin kit and CLIA method and the obtained results were analyzed by SPSS version 16.
The mean age of the normal group was 26.75± 4.96 and the mean age for those with gestational diabetese was 27.07± 5.73 .( p = 0.7) .BMI index was the same for both groups and the average vitamin D serum levels for normal and patient groups were 11.06±17.81 and 17.41±6.76 nmol/l , respectively. Using regression logistic model, we demonstrated that increasing vitamin D serum level can reduce the chance of gestational diabetese by 5%. OR=0.95 (CI=0.91-0.99)
In conclusion, gestational diabetese and vitamin D level seem to be negatively correlated. (P=0.002)