فهرست مطالب سمیه رجب پور

The use of antibiotic prophylaxis in the treatment of burns is a controversial issue. Many specialists start antibiotic treatment after the patient is admitted to prevent infection, while in most cases, antibiotic use is not necessary. The aim of the present study was to determine the relationship between the use of antibiotic prophylaxis on mortality, infection and drug resistance in burn patients without sepsis symptoms admitted to Amir al-Momenin Burn Injury Hospital.

The present analytical-cross-sectional study was conducted in 2020-2021 at Amir al-Momenin Burn Injury Hospital, Shiraz, Iran. 2982 patients were included in the study. Patients' information, results of bacterial culture and antibiotic resistance of isolated isolates were extracted from burn patients' registry system and health information system. Descriptive statistics and the collected data were presented in tabular form. Quantitative data were summarized as mean and standard deviation and qualitative data as frequency and percentage graphs. Statistical analysis was analyzed for the association of results using paired t-test and chi-square. The level of statistical significance in all tests was considered P≤0.05.

Antibiotic resistance in hospitalized patients with prophylaxis treatment was 54.30%. The rate of mortality and re-hospitalization of patients in patients with no antibiotic prophylaxis was zero; In addition, the blood, liver and kidney factors of the patients were within the normal range. There was no significant difference between platelet levels, alkaline phosphatase serum level, alanine aminotransferase, blood urea nitrogen level and its ratio to creatinine (P≥0.05) on the first day of hospitalization and at the time of discharge. On the other hand, there was a significant difference between the levels of white blood cells, neutrophils and albumin (P<0.001) in the first three days of hospitalization and the time of discharge.

The use of prophylactic antibiotics had no effect in the treatment of burn diseases without infection, and in order to reduce microbial resistance, it is better to avoid unnecessary use of antibiotics in burn areas.

The present study was conducted with the aim of investigating the effectiveness of unified transdiagnostic group therapy on cognitive emotional regulation in patients with anxiety disorders. The current research was semi-experimental with a pretest-posttest design and a control group. The statistical population of the research included all individuals with anxiety disorders referred to one of the clinics in Mashhad, who had been referred to this clinic for treatment from October to December 2022. 30 participants in this research were selected from about 100 patients by voluntary sampling method and were replaced in two experimental and control groups. Subjects in two stages of pre-test and post-test with Anxiety Inventory (BAI) Beck et al. (1988) and DSM-5-TR diagnostic criteria, Persian version of the Cognitive Emotion Regulation Questionnaire (CERQ-P) Garnefski & Kraaij (2006) were measured. The intervention group received 8 sessions of 90 minutes as one session per week of unified transdiagnostic treatment. Data analysis was done using multivariate covariance analysis. Data analysis showed that by controlling the effect of the pre-test, there was a significant difference at the level of 0/05 between the post-test mean of cognitive emotional regulation including self-blame, rumination, catastrophizing, other-blame, acceptance, positive refocusing, refocus on planning, positive reappraisal and putting in the two experimental and control groups. Therefore, it can be concluded that group-based Unified transdiagnostic therapy can be effective in cognitive-emotional regulation.

Birth weight is a major indicator of infant health. Infants with low birth weight face high risk of disability and a number of other medical and psychological problems more than infants with normal weight birth. Given the importance and the role of low birth weight in the mortality and morbidity of neonates and the costs of care, the aim of this research was to investigate the role of biological - environmental characteristics of pregnant mothers on Birth weight. The study employed a Causal-comparative design. The study population consisted of all mothers who gave birth in Quechan-Iran from October 2015 to September 2016. The sample consisted of 70 infants, who were selected by convenience sampling from population.  Criteria for participation in this study was to give birth to infants born alive with birth weigh less than 2500 gram and exclusion criteria was incomplete questionnaires by mothers. The data was gathered by a questionnaire. A number of statistical procedures including ANOVA and Chi square tests were used to test the research hypotheses. Finding of Fisher test showed that history of abortions during pregnancy had significant difference on weight of birth in infants (P>0.001 ), The weight of infants with mothers who had not history of abortions during pregnancy were more than weight of infants whose mothers had history of abortions during pregnancy. Finding of Chi square test showed that history of high blood pressure during pregnancy had significant difference on weight of birth in infants (P>0.001). On the other hand, The weight of infants with mothers who had not a history of high blood pressure during pregnancy were more than weight of infants whose mothers had history of high blood pressure during pregnancy. The results of chi square test showed that history of trauma during pregnancy had significant effect on birth weight (P>0.001). The weight of infants with mothers who had not a history of trauma during pregnancy were more than weight of infants whose mothers had  a history of trauma during pregnancy. The results showed factors associated between low birth weights were history of high blood pressure and a history of trauma during pregnancy. Thus, the etiology and identification of biological factors associated with low birth weight is recommended.