سکینه نیک سرشت

Adiponectin is a hormone that plays an important role in diet-induced insulin resistance. People with higher weight have a lower adiponectin levels and are more susceptible to type II diabetes. Studies have shown that exposure to altitude and hypoxic environment causes weight loss. The aim of this study was to investigate the effect of intermittent hypoxia on adiponectin level and BMI in obese people with type II diabetes. Ten obese subjects with type II diabetes participate in the study with mean BMI of 32.02 ± 2.47 and age range of 50-70 years old. The intervention consisted of 14 sessions of intermittent hypoxia, one hour per day for 14 consecutive days. Plasma adiponectin and BMI were measured three times (pretest, day 7, and posttest) and two times (pre- and post-tests). Plasma adiponectin showed a non-significant 2.1% reduction, 6 days after intermittent hypoxia intervention (day 7) (t9= 1.06; p=0.317). Also, in fifteenth day or after 14 days of intermittent hypoxia intervention, plasma adiponectin levels had a 5% non-significant reduction compared to the pretest (t9= 0.578; p=0.577). The results of present study also showed that short-term (7 days) and medium term (14 days) exposure to intermittent hypoxia had no effect on BMI (p> 0.05).Discussion & Findings of present study indicate that performing 6 and 14 one-hour sessions of intermittent hypoxia in consecutive days cause no significant effect in plasma adiponectin and BMI of obese people with type II diabetes.

Obese peoplewill beaffected by respiratory problems and impaired pulmonary function parameters because ofmore fatin thetrunk andmore pressure on the respiratory system. The aim of this study was to evaluatethe effects of 15 days of intermittent hypoxia on pulmonary functiontest inobese patient with type 2 diabetes. 7 obese subjects(1man,6women) with type II diabetes, with mean BMI of 32.42 ± 1.06 and the age range of 50-70 years, volunteered to participate inthestudy. The intervention consisted of 15 sessions of intermittent hypoxia, one hour per day, for fifteen consecutive days.pulmonaryfunction parameters including: VC, FVC, FEV1,TV, PEF, FEF25-75%, MVV and BMI and VO2max in pre- and post-tests were measured. After 15 days of intermittenthypoxia VC, TV, FEV1, MVV, FVC, FEF 25-75% were not changed significantly.However, PEF and VO2max had significant increases of 6.5% and 13%, respectively(p<0.05), furthermore BMI had a nonsignificant decrease of 3.5%. Discussion & Findingsofthis studyindicate that despite positive effects of intermittent hypoxiaonVO2max and PEF,BMI and other pulmonary parameters not significantly change after 15 consecutive sessions of intermitent hypoxic exposure.