شبنم سوهانیان

Denture stomatitis is a chronic infectious lesion caused by Candida albicans along with other oral microflora in patients wearing dentures. A substance with fewer side effects should be established for the treatment of this lesion since it may lead to secondary complications for the patient. The present study was conducted by selecting and dividing 31 patients with denture stomatitis into case and control groups. Propolis mouthwash and Placebo were prescribed in the case and control groups, respectively. The participants were evaluated according to the severity of the lesions based on the clinical examination which was recorded in the datasheet by the examiner on the first, fifth, and tenth days after the start of the study. The results were statistically analyzed by SPSS software (version 24.0) using Shapiro-Wilk, Fisher’s Exact, One-Way ANOVA, Kruskal-Wallis, Friedman, and Bonferroni tests. A P-value less than 0.05 is statistically significant. The two groups were homogeneous in terms of age (P=0.282), gender (P=0.890), and denture stomatitis severity (P=0.203) at the beginning of the study. However, the improvement of denture stomatitis in the case group was significant compared to that of the control group after 5 days (P=0.014) and 10 days (P<0.001). The results displayed that the severity of the lesions significantly reduced in patients who received Propolis mouthwash. Consequently, Propolis simultaneously offers antibacterial, antifungal, antiviral, and anti-inflammatory properties, and it relieves denture stomatitis without any side effects. Therefore, it can be recommended to physicians as a routine medication.

Tooth decay is the main cause of pulp and periapical diseases, and when the pulp involves the tooth, there is no other choice but to drain the pulp to save the tooth. The emergence of new methods of regenerative treatments has made it possible to restore dental pulp and dentin. Since regenerative treatments have been limited to immature teeth, this study was conducted to regenerate mature pulp tissue by dental pulp stem cell transplantation along with Platelet Rich Plasma (PRP) Matrix in rabbits.

This experimental pilot study was conducted on a maxillary central incisor in a 1-year-old 2kg adult male albino rabbit. After completely cleaning the pulp tissue from the root and crown and washing the root canal, File #30 was passed through the apex to cause bleeding. Then dental pulp stem cells along with PRP were injected into the canal and the crown was sealed with glass ionomer cement. After 14 days, a radiograph was taken from the tooth, the extracted tooth was stained by hematoxylin-eosin and examined by light microscope.

In the histological examination, in the inner wall of the root canal of odontoblasts, small thickness was observed in tubular dentin (about 1 mm) and pseudovascular structures. Furthermore, the entire space of the root canal was filled with a small and scattered number of inflammatory cells and pulp-like living tissue.

Based on the results of this study, the observation of pseudovascular structures indicates the regenerative potential of dental pulp stem cells and opens a window for studies with more samples to effectively regenerate the dental pulp.

Determining the prevalence of various diseases in different communities is one of the first measures to improve the level of education, prevention and treatment of diseases. Occasionally, first symptoms of some diseases appear in mouth, so, timely diagnosis made by dentists is of particular importance. The aim of this study was to determine the frequency of oral mucosal lesions and some related factors in patients over 12 years of age in Oral Medicine Department affiliated with Semnan Dental School in 2017-2019.

In this descriptive study, all individuals aged 12 years and older (n=1001) were investigated. Data, including gender, age, oral lesions, smoking, and wearing dentures were recorded in a checklist and analyzed in Chi-square test in SPSS V26.

In this study, 1001 people including 420 men and 581 women were studied. Frequency of oral lesions was 78.5%. The most common lesions were coated tongue (36.5%), gingivitis (34%), and periodontitis (28.4%). There was a significant relationship between age and oral lesions (P< 0.001). Total frequency of lesions was significantly higher in smokers (P= 0.016). Among the patients, 98.8% were unconscious about their oral lesions.

Relatively high frequency of oral lesions and lack of awareness of their presence in people studied indicate the necessity for periodic oral mucosal examinations and dental examinations.

The field of Oral and Maxillofacial Medicine is a relatively young specialty and in this study we evaluated the knowledge of Physicians, Dentists and Patients towards the fields of activity of Oral and Maxillofacial Medicine in Semnan.

In this descriptive-analytical study, a questionnaire in various fields related to Oral and Maxillofacial Medicine Specialty designed and after confirming the reliability and validity, provided to 400 adult literate patients referred to Semnan Dental School and Kowsar Hospital, General Practitioners, Specialist Physicians, General Dentists and Specialist Dentists. The sampling method was census and software used for statistical analysis was SPSS with different data analysis methods including Kolmroof-Smirnov, Mann-Whitney, Kruskal-Wallis and Chi-square tests being used with a significant level of 5%.

Analyzed data showed that Patients in the field of treatment plan and referral (25%), General Practitioners and Specialist Dentists in the field of diseases (34.25%, 31.8% respectively) and Salivary gland tumors (9.15%, 15.9% respectively), Specialist Physicians in the field of Oral Surgery (22.1%), General Dentists in the field of Dental services to medically compromised patients (33%) had the least awareness.

In conclusion, special attention should be paid to the future educational planning for each target group, in the field which has the least awareness.

Xerostomia is a distressing complication of diabetes that can reduce the quality of life of the patient, which is largely due to poor blood sugar control and medications that decrease the function of the salivary glands. Conclusively, the aim of this study was to investigate the association of Blood Sugar Control on Unstimulated Saliva and Xerostomia.

In this study, 30 diabetics (Fasting Blood Sugar (FBS) ≥126mg/100ml), 30 pre-diabetics (FBS 110-126mg/100ml) and 30 healthy individuals (FBS <100mg/100ml) were selected from the patients who were referred to the Kowsar Hospital of Semnan after obtaining informed consent. The demographic information, level of FBS, HbA1C and unstimulated Saliva was evaluated and data were statistically analyzed.

According to the HbA1c results, the mean standard deviation of unstimulated saliva in controlled diabetic group was 0.08 0 ± 0.02 ml/min and 0.06 ± 0.02 ml/min in uncontrolled group, which indicated a significant difference (P=0.006). Unstimulated saliva in diabetic patients was 0.02 ± 0.07 ml/ min and ± 14.0 ± 02.0 ml in the control group (P<0.001).

Elevating FBS decreases unstimulated saliva and on the other hand increases Xerostomia. Since patients with uncontrolled diabetes have more dry mouth, blood sugar levels and its control has a significant effect on reducing unstimulated saliva and Xerostomia.

Psoriasis is a chronic inflammatory genodermatosis, and periodontitis is an inflammatory disease of the protective tissue of the tooth. There is increasing prevalence of psoriasis and periodontitis and some studies indicated a relationship between psoriasis and periodontitis. The purpose of this investigation was to study the frequency and severity of periodontitis in patients with psoriasis.

In this study, the severity of psoriasis and mouth and teeth examination results of 40 patients were recorded. Tooth looseness, number of missing teeth, bleeding on probing, and clinical attachment loss were measured using periodontal probe. Data analysis was carried out applying t test, Chi square, and correlation coefficient.

The overall prevalence of periodontal diseases was 80%, including loose teeth (10%), missing teeth (47.5%), gingival bleeding (60%), and gingival resorption (62.5%). Periodontal diseases were found to be significantly associated with duration and severity of psoriasis (P = 0.032 and P <0.001, respectively). Also, there was a significant association between severity of periodontal diseases and duration and severity of psoriasis (P = 0.048 and P = 0.023, respectively).

According to this study, periodontal diseases are highly prevalent in patients with psoriasis which are associated with severity and duration of psoriasis. Inflammatory process is involved in both diseases, so, accurate oral examinations for periodontal diseases are strongly suggested in patients with psoriasis.

Research is one of the major fundamental in the development of human societies. Failure understanding and awareness of the goals of research programs including essential tools that should be delivered to policy makers of research.
This descriptive cross-sectional study was carried out to determine barriers to research from viewpoint of faculty members of the School of Dentistry, Babol University of Medical Science in 2015. To collect data, a questionnaire consisted of demographic and items in five-point sets up. To analyze the data, related statistical tests were used. SPSS version 20 software used and significant level was considered 0.05.
FINDINGS: Socio-cultural field with highest score was the most barrier field and compiled project field with lowest score known as lowest barrier between other fields. Mean score of items between of the field of compiled project and socio-cultural with other fields, mean score of items of socio-cultural field between males and females and mean score of items of compiled project and socio-cultural fields between different educational groups showed significant statistical difference.
Researchers in any scientific discipline according to their own experiences and other researchers, must reveal weaknesses and shortcomings. So are recommended research managers take action by results of this research in removing barriers to research and promote the university level.

Plexiform schwannoma is a type of schwannoma that can be occured at any age and any site of the oral cavity. In the gross and histopathological features, it shows plexiform or multinodular growth pattern. This variant of schwannoma is sometimes associated with neurofibromatosis type II or schwannomatosis. Histopathologically, plexiform schwannoma is composed of schwann cells that show Anthony A growth pattern. Mitosis are rare or absent.This study reports a case of a healthy 34 year old female with swelling in floor of her mouth; according to the clinical and histopathological findings, the diagnosis was Plexiform schwannoma.