شیما محمدی

Sepsis is one of the leading causes of death in intensive care units (ICU) and is becoming more prevalent globally. As a result, an accurate and timely diagnosis of sepsis is critical for selecting the best treatment to prevent disease progression and mortality. In this study, CRP and TNF-α as common biomarkers of sepsis were detected using a label-free optical biosensor based on interferometric Fourier transform spectroscopy from a porous silicon substrate. The porous silicon layer was chemically modified with APTES and glutaraldehyde to immobilize the aptamer covalently in order to capture the analyte. The refractive index of the porous layer was determined by analyzing the reflection spectrum from the porous layer, which was associated with different biomarker concentrations. The results demonstrated linear responses in concentrations ranging from 10-10000 ng/ml for CRP and 100-10000 ng/ml for TNF-α and the biosensor's high discrimination. Thus, it has a high potential for advancement in clinical sepsis diagnosis.

In this study, human rights in Islam and the West discussed the legal system and the place of religions from the perspective of human rights be addressed. To overview the objectives and activities related to human rights and the teachings of divine religions and the main message is found. Basically, the teachings of divine religions have been very effective role in promoting human rights. The most important problems and disagreements in connection with the Universal Declaration of Human Rights, there is the issue of absolute freedom to choose and change religion and promote the full equality of women and men, the requirements of true morality and public order that the Islamic Human Rights and West of religions discussed human rights in a way that is not forced to choose a religion support. Attitude that this article seeks to answer it.

Ants are the most ubiquitous insects on the earth with more than 12000 species which are classified into 21 subfamilies. Until now, more than 170 ant species have recorded in Iran. Mutualistic relationship between ants and scale insects have been reported in Iran. Such relationships between ants and insects are known as trophobiosis which is due to attraction of ants to honeydew of scale insects. Honeydew is a sugar-rich sticky liquid, secreted by aphids and some scale insects as they feed on plant sap. Ants provide protection from predators and parasitoids by building shelters around scale insect colonies. Such a relationship is mostly facultative and only a few taxa of mostly tropical or subtropical scale insects have obligate mutualism with ants. The coccoids with obligate mutualism display obvious behavioral and morphological adaptations for living with ants. Ants are also able to establish antagonistic interaction with honeydew-producing hemipterans and contribute positively to biological control by the suppression of pests.

In a study during 2013-2014, colonies of the mealybug Paracoccus ficus Moghaddam, 2014 were investigated for mutualistic ants feeding on honeydew of the mealybug in fig orchards of Neyriz, Estahban and Shiraz cities of Fars province, South Iran. Samples were collected by hand, forceps and soft brush. The specimens were preserved in 75% alcohol in small glass vials and were transferred to the laboratory. The morphological keys were used for identification. Specimens were deposited in Insect and Mite Collection of Ahvaz, at Department of Plant Protection, Shahid Chamran University of Ahvaz.

Totally, 6 species belonging to 3 subfamilies of ants were identified as follows:Myrmicinae: Monomorium abeillei Andre, 1881; Tetramorium sp.; Pheidole pallidula Nylander, 1849; Crematogaster antaris Forel, 1894; Formicinae: Cataglyphis lividus Andre, 1881; Dolichoderinae: Tapinoma simrothi Krausse, 1911.
Among collected species, T. simrothi and P. pallidula were more frequent. T. simrothi has also recorded as most frequent mutualistic ants with aphids in Central Iran. Natural enemies exploit hemipterans which receive ant protection for their benefit. For example, some parasitoid wasps soliciting honeydew directly from aphids by antennation and mimicking ants during foraging in host patches. Researchers believe that preventing ants from colonies of Pseudococcidae scale insects is necessary for success in biological control of such pests. However, not all of ants have negative effects in biological control of pests. Predatory ants are less attracted to the honeydew and mostly feed on egg, larvae and adult insects. Moreover, some ants are important in pollination, soil improvement, and nutrient cycling.  

Behavioral and ecological should be carried on ants in pest management programs, and only if they have a negative influence on biological control of scale insects, then perform control measures for ants.

Thyroid dysfunction and rheumatoid arthritis (RA) are autoimmune diseases that can cause many problems and complications in patients. Accordingly, this study aimed to investigate thyroid disorders in patients with rheumatoid arthritis.

Thyroid hormones, including TSH, T4, and T3, were measured by radioimmunoassay. Following that, thyroid antibodies, including Anti TG Ab and Anti TPO Ab, were measured by ELISA. The data were analyzed in SPSS software through the Chi-square test, Fisher test, and t-test.

The results of statistical analysis show that there is a significant difference between the two groups in terms of the prevalence of hypothyroidism. Also, the results of this study show that there is a statistically significant difference between the two groups in terms of Anti TG, Anti TPO, RF, Anti CCP and also in terms of Free T3. On the other hand, the results of statistical analysis for TSH and Free T4 showed that there was no significant difference between the case and control groups.

Overall, the results of this study indicate that there is a higher prevalence of thyroid dysfunction in RA patients, especially hypothyroidism. It is recommended that thyroid tests and examinations be included in the evaluation of rheumatoid arthritis patients. Further studies are also suggested to clarify the underlying mechanisms of the relationship between rheumatoid arthritis and thyroid dysfunction.

The present study aimed to evaluate the barriers to general medicine dissertation implementation in Zahedan University of Medical Sciences from the perspective of faculty members in 2017.

In this descriptive study, a self-administered questionnaire was distributed among 100 faculty members of Zahedan University of Medical Sciences using census method and 80 questionnaires were completed. Data were analyzed using Chi-square test.

49 (62.7%) of supervisors presented inadequate education of students in literature review, 32 (41.8%) lack of sufficient information about research priorities of the country, 29 (32.8%) lack of student guidance in theses writing (p=0.018) and 39 (46.3%) the statistical analysis of the results and their misunderstanding by the student as the main problems.

The results showed that the most important obstacle for faculty members was inadequate education of the students in the review of literature and articles. In this regard, holding research methodology workshops can be effective.

Flowers number and quality of olive tree is the main factor which influence on fruit and oil yield. On this case, water limitation during flowers differentiation and development in winter can reduce productivity by increasing incomplete flowers. Therefore, one of the most important times for irrigation where there is not enough rainfall in the late winter is one month before flowering, which unfortunately usually does not pay attention enough. Therefore, in this study, effect of winter irrigation with three (WI3), six (WI6) and nine days (W19) on flowering, fruit set and fruit and oil yield of two olive cultivars, Zard and Manzanilla was investigated. Rain fed irrigation (Rain fed) and common irrigation schedules in the orchard with, seven days (Control) were as a control. Irrigation of trees in treatments was performed from January to mid-April for three and a half months. The characteristics such as inflorescence number and length were measured from four main branches in each tree. Thereafter, total flowers number, complete flowers and final fruit set after natural flowers abscission was determined form six secondary shoots in each main branch. Fruit yield per tree in each treatment was calculated after fruit maturation. Furthermore, oil yield was measured after oil extraction. The Results showed there was a significant difference between different irrigation treatments for number of inflorescences, number of flowers, complete flowers, final fruit set percent, fruit yield and oil yield and fruit weight was not influence by irrigation. The best winter irrigation interval was dependent to olive cultivars so that The lowest inflorescence number, total flowers numbers, complete flowers and final fruits was found in rain fed olive tree and the highest values inflorescence number, total flowers numbers, complete flowers was found after six days interval for cv Zard and after nine days interval for cv Manzanilla. There was no significant difference between winter irrigation treatments for fruit yield, but there was a significant with rain fed tree. The highest values fruit yield was found after six days interval. Winter irrigation increased fruit yield by about 35 percent and increased oil yield by about 50 percent compared to rain fed treatment, the highest fruit yield was found after six days winter irrigation interval and highest oil yield was found nine days winter irrigation interval. Overall, winter irrigation in olive orchards could increase fruit and oil yield by increasing complete flowers number, final fruit set percentage, oil yield, and fruit weight.

In children with attention deficit hyperactivity disorder, defects in executive functions are also recognized.The aim of this study was to measure the effectiveness of cognitive rehabilitation on improvement of executive function of response inhibition in children with attention deficit hyperactivity disorder (ADHD). Methode: The present study was semi-experimental design with pre-test and post-test with control group. In this study, children aged 7 to 12 years who were diagnosed with (ADHD) by psychological experts of the counseling center of Kermanshah were selected. 20 of these children (10 girls and 10 boys) were randomly assigned to two experimental and control groups. The experimental group was subjected to 12 sessions of The Captain's Log Mind Power Builder and the control group did not receive treatment. After the last session of treatment, both groups were re-evaluated. Data were analyzed by covariance analysis using SPSS_23 software. The findings showed that cognitive rehabilitation was effective on improvement of executive function of response inhibition in children with attention deficit hyperactivity disorder. Therefore, we recommend a cognitive rehabilitation program for improving the executive function of response inhibition of children with ADHD.

Background and Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases and is closely associated with impaired insulin signaling and glucose metabolism in the brain. Ziziphora tenuior exhibits antidiabetic effects and antioxidant and memory augmenting properties. For this reason, the aim of this study was to investigate the effect of hydro-alcoholic extract of Ziziphora medicinal plant on the progress of Alzheimer's disease.
In this experimental study, 42 male wistar rats (270 ± 20 gr) were divided in five groups (n = 6): control, sham, Alzheimer, Alzheimer saline and Alzheimer Ziziphora (3 groups). For Alzheimer induction, streptozotocin was injected intracerebroventricular (ICV) and after that, rats received Ziziphora daily (100, 150, 200 mg/kgBW) for 21 days. The Morris Water maze was used for studying the spatial learning memory. Data were analyzed by SPSS software and ANOVA and Tukey's post-test.
Findings: Intraventricular injection of streptozotocin damaged the spatial memory. Pretreatment of Ziziphora (100, 150, 200 mg/kg; 21 days) significantly (p Based on the results, treatment of rats with hydro-alcoholic extract of Ziziphora can help prevent spatial memory loss during Alzheimer's disease. The extract of this plant can be improved cognitive processes through positive effects on neurological function and probably had been a significant role in the prevention and treatment of neurological disorders.

Brain ischemia is one of the leading causes of death and physical disability worldwide. Flavonoids found in Raspberry fruit (RF) play an important role against oxidative stress injuries in the biological systems.
The present study was carried out to evaluate the effect of RF on ischemia/reperfusion (I/R)-induced brain injury in rats.
In the present experimental study, 42 wistar adult male rats weighing 200–250 g were divided into six groups as sham operated (Sh), ischemia/reperfusion (I/R) received normal saline (I嗨), I/R groups treated with RF extract (I, 50, 100, or 200 mg/kg, IP, respectively). The global cerebral I/R was induced by occluding bilateral common carotid arteries for 30 min, followed by reperfusion. Behavioral test performed with shuttle box and analgesia test performed with tail flick test.
Administration of RF extract 50, 100, or 200 mg/kg doses increased passive avoidance memory significantly (P Results of this study showed that RF extract possesses protective effects against pain and memory deficits induced by I/R, which may be due to its anti-inflammatory and antioxidant effects.

This study aimed to investigate the effectiveness of sexual health behaviors training on sexual dysfunction of addicted women.
A semi-experimental research method with pre-posttest with witness group design was used. The research population included all women were recovering addict in rehab centers of Attar, Sepahan, Pake Mehre and Conger 60 in 2015 in Isfahan. To select a sample, voluntary method was used and administering of the questionnaires, from 100 volunteers, 30 patients were selected and assigned randomly in two groups (n = 15) and witness (n = 15). Experimental group was under 8 training sessions, each one 90 minutes. The witness group did not receive any intervention.
The results showed that sexual health behaviors training have a significant effect on sexual dysfunction of addicted women and its components.
It can be concluded, sexual health behaviors training education can reduce sexual dysfunction of addicted women. So this method can be used in addiction treatment centers for women.

Polycystic ovary syndrome (PCOS) is the most common cause of infertility and endocrinopathy in women due to lack of ovulation. Silymarin has anti-inflammatory properties and is a modulator of the immune system. In this experimental study, the effect of silymarinon PCOS-induced rats was studied. In this experimental study, 144 adult Wistar rats were divided into groups of control, sham, PCOS (S.C. injection of 2mg estradiol valerate/ rat, once) and treated with silymarin. After induction of PCOS during 60 days, 20, 50, 100, 200 and 300 mg/kg BW silymarin was injected intraperitoneally for 10 days. Sham and control groups received DMSO and no injection, respectively. All groups were anesthetized and the serum and ovary of groups were collected in order to investigate the histological and serologic changes. Data were tested using ANOVA in Instat software and P <0.05 was considered significant. PCOs induction resulted in elevation of follicular cyst formation, abnormal follicular development and increasing of androgen compared with control rats. Silymarin attenuated ovarian cysts and thickness of theca layer and improved hormonal balance and follicle development in PCOS rats. Silymarin can reduce the histological and hormonal symptoms of PCOS, and has a protective effect on ovary. It seems that this potency is due to the antioxidant and anti-inflammatory effects of silymarin, which can reduce cyst counts and improve the development of ovarian follicles.

Polycystic ovary syndrome (PCOS) is a syndrome with complex endocrine and metabolic disorders, which is characterized by chronic anovulation, polycystic ovary and hyperandrogenism. Curcumin is a substance with antioxidant and anti-inflammatory effects. This study aimed to examine the therapeutic effect of curcumin on polycystic ovary syndrome in adult rats. In this experimental study, PCOS was induced in adult female Wistar rats (170 g) by subcutaneous injection of estradiol valerate (2 mg/kg). The control group received no injection. At the end of 60th day, the rats were divided into control, PCOS and curcumin-treated PCOS (100, 200, 300 and 400 mg/kg) groups. After 14 days of intraperitoneal curcumin treatment, blood and ovary samples of all groups were taken for histological and serological studies. The thickness of the theca layer, primordial follicles and number of cysts were significantly decreased in high-dose curcumin treated ovaries compared to the PCOS group. Moreover, the appearance of corpus luteums as the main sign of recurrent ovulation was established. The serological analyses showed an increase in FSH and progesterone and a decrease in LH, estradiol and testosterone compared to the PCOS. The results indicate that curcumin may be a useful agent for improving the PCOS and initiation of ovulation through its various antioxidant and anti-inflammatory effects.