فهرست مطالب علی کربلایی مهدی

Tissue engineering approach using the combination of stem cells and nanofibrous scaffolds has attracted the interest of research community for regeneration applications.
In this study, PANi/PCL/Gel composite nanofibrous scaffold was fabricated by electrospinning. Plasma treatment technique was used for the surface modification of nanofibers. Contact angle technique and scanning electron microscopy (SEM) were used for characterization of electrospun nanofibers. Growth and proliferation of the cells as well as the biocompatibility of nanoscaffolds were evaluated by MTT assay.
The results of the contact angle technique showed the surface modification of electrospun nanofibrous scaffolds. The MTT results showed that the synthesized nanofibers did not have any toxic effect and promoted the growth and proliferation of fibroblast cells. SEM images confirmed the adhesion and biocompatibility of nanofibers.
Our results suggested PANi/PCL/Gel electrospun nanofibers as a biocompatible composite for the regenerative medicine.

Molecular imaging is one of the main focuses in medical diagnostics. Nanoparticles allow us to effectively imagine the various component of molecule with high contrast. Different factors have been discussed about contrast agent nanoparticles. Moreover, some of the most important samples have been highlighted in the present study.
Methods and Materials: This research is a theoretical study and analytical method that was performed by searching Nanotechnology, Molecular imaging, Drug delivery methods, Gene therapy and contrast agent nanoparticles keywords in Google scholar, Science direct, Pubmed and Scopus websites in terms of content (content analysis). This article was written based on 10 chosen articles which were found after the search in the internet websites.
Most of the nanoparticles in this study have been used to produce the new contrast agents, in particular, for molecular imaging and diagnostics cellular processes. The benefits of using these nanoparticles contain: ability of producing high contrast, ease of integration into multiple properties, long time circulation in the blood and ability of carrying high volume (such as drugs). Principles and methods of producing nanoparticles have been improved over the recent years; therefore, the more complex samples of Nano sized contrast agents have been reported such as the: paramagnetic particles, macrophages quantum dots, quantum dot, and devices that can deliver material to the atomic and molecular sections. In addition, Micro-MRI has been used to survey vascular and drug delivery.
Discussion and The usage of contrast agent nanoparticles provides more details about the processes and effects of a disease. Making these materials has significantly improved in the resent years by creating various functions in them. However, there are many areas for the improvement in biocompatibility, effectiveness, specific features and diagnosis. Generally, the contrast agent nanoparticles can be synthesized for specific performance and specific applications.