غلامرضا حاجیانی

Blood safety is one of the basic goals of blood centers in the world. Confidential self-exclusion system is used with routine diagnostic tests to detect transfusion transmitted infections. This study aimed to investigate efficacy of these systems onimprovement of blood safety in Bushehr Blood Centers. In this retrospective study the rate of confidential self-exclusion was compared among regular and first-time blood donors of Bushehr province. Data were collected from Bushehr Blood Transfusion Organization. Chi-square test was used for data analysis. In this study from a total of 39921 blood donors، 909 cases (2. 1%) were determined as confidential self-exclusion; 64. 4% of them were first time donor. All HIV positive patients had excluded their blood. The results revealed that the self-exclusion method is an appropriate way to increase blood safety. It has also indicated that it is possible to exclude infected donors during incubation period.

Hepatitis C is one of the main causes of mortality and disability of liver diseases worldwide. Main transmission rout is blood transfusion and its epidemiology is changing due to increasing injecting drug users. It is also important because of co-transfer with HIV. In order to finding common HCV genotyping and transmission risk factors, we conducted this study on HCV positive patients who was referred from Bushehr Blood Transfusion Organization. A total of 69 patients who were detected as positive for HCV antibody (by using ELISA method and RIBA test) referred to virology laboratory between 2007-8 in order to collecting demographic and epidemiologic data, molecular diagnosis and furthermore virus genotyping. After detection of HCV, RNA genotyping of virus was done by using genotype specific primers (By PCR-RFLP). From 69 HCV positive patients 60 had positive RT PCR. Male/Female ratio was 11. Genotype of 38.3% & 36.7% of them was 3a & 1a respectively. The most important transmission risk factor was intravenous drug using (IVDU), the second rout was iatrogenic (dentistry, blood transfusion & medical intervention). There was an association between genotypes & risk factors. Genotype 3a was associated with IVDU & 1a with iatrogenic routs (p<0.05). Co-infection with HBV & HIV was found in 8.3% of patients who all were IV drug users. The dominant genotype of HCV in Bushehr was 3a & 1awith similar dispersion in European countries. The dominant route of transmission is injection of drugs and it shows the necessity of intervention and education in this group of patients.

Hydrogen peroxide is an unstable colorless heavy liquid used as bleach in industry and as an antiseptic in house holds. Teaching human anatomy at any level relies not only on the expertise of a tutor but also on the availability and use of good teaching aids. Plastination specimens have unique position as teaching aids to exhibit accurate anatomical structures and they are also easy to store and handle by students. Darkening of plastinated tissue is one of the problems that may occurr because dark tissue is unusable. We applied this survey to examine clearing of the hydrogen peroxide on posterior wall of trunk spinal cord and medulla oblongata before Plastination. This study was carried out on a human body after fixation dissection dehydration and defatization of the cadaver. The hydrogen peroxide was prepared in several concentration (33.3%16.6%8.3%4.1%) was added to the specimen of master specimen at several times (1 2 468101218 and 24 hours) for clarification. We choused (16.6% per 6hour) as the best situation for clarify of specimen. After clarification of original specimen impregnation and curing was carried out. Finally the prepared Plastinated specimen was compared with the standard Plastinated model. The obtained Plastinated specimen was compared with the standard model of Heidelberg Germany for appearance and resolution. The plastinated specimen obtained was compared with the standard model of Heidelberg Germany for its stature flexibility and traction by the universal test DARTC (England) apparatus in the Department of Medical Physics Isfahan School of Medicine. The result obtained was found to show that the P-value was. 08 and the standard error was (-0.460±0.382). The Plastinated specimen prepared provides an excellent opportunity to demonstrate and study the dissected areas of the difficult structures which can be of great benefit in teaching gross anatomy and neuro-anatomy In addition because of the durability safety reduction intoxic and noxious fumes of formalin the Plastinated specimens can be unique materials as a teaching aid by the side of (Wet) specimens.