مریم نوبخت راد

This study examined changes in lipid profile in patients with severe sepsis and septic shock in comparison with non-sepsis patients admitted to the medical ICU and its association with mortality. Through sampling of internal ICU admitted patients in Seman Kostar hospital, patients were divided into two groups of sepsis (n=107) and non-septic (n=115). Then, serum level of total cholesterol, triglyceride, HDL and LDL with specific kit was evaluated randomly at first and fifth day after ICU admition.Then, two groups was compared. In sepsis and non-septic groups, 51.4% and 47% were men and the remainder was women, mean age was 74.2 and 68 years, mortality rate was 76.6% and 46.9%, respectively. In the first instance, compared with non-septic, lipid variables except triglycerides and cholesterol decreased significantly and in the second instance, cholesterol, triglycerides and LDL reduced and HDL increased. HDL in sepsis and TG at fifth day and LDL at fifth day in non-septic group was associated with mortality rate. Patients with severe sepsis and septic shock had lower levels of serum lipid profiles compared with patients without sepsis in ICU. Serum HDL in sepsis and LDL and TG in non-septic patients had prognostic role.

To evaluate anophthalmic socket complications and the incidence of sympathetic ophthalmia among individuals who had undergone primary enucleation or severe ocular trauma during the war between Iran and Iraq. All monocular veterans of the mentioned war in Khorasan province, Iran were recalled during a 7-month period. Preliminary data including age at the time of injury, occupation, previous operations and ocular symptoms were evaluated and all participants underwent a complete ophthalmologic examination particularly regarding the anophthalmic socket, orbital implant and prosthesis condition. Overall, 135 male individuals participated in this study. Mean age was 42±7 years and 86% were 30-50 years. Patients had undergone complete enucleation in 39 (28.9%), partial enucleation in 21 (15.6%) and evisceration in 6 (4.4%) cases. In 34 cases (25.2%) pthisis bulbi had occurred after trauma and the type of surgery was not identifiable in the remaining 35 cases (25.9%). The most common symptom in injured eyes was mucoid or mucopurulent discharge (71%). Common complications in 101 subjects with previous operations were superior sulcus deformity (72.3%) and socket contracture (44.5%). Socket motility was satisfactory only in 18%. All signs of the anophthalmic syndrome are more severe and more prevalent among enucleated cases secondary to war injuries. Due to the rarity of sympathetic ophthalmia, we suggest enucleation and orbital implantation in an elective setting.